Apolipoprotein E Gene Polymorphism, Glycated Hemoglobin, and Peripheral Arterial Disease Risk in Chinese Type 2 Diabetic Patients
المؤلفون المشاركون
Feng, Tongbao
Hu, Yujing
Ling, Tinghuan
Yu, Min
Bai, Yang
Zhang, Ping
Wang, Yan
المصدر
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-03-10
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Background.
The apolipoprotein E (ApoE) gene polymorphism has been found to influence plasma lipid concentration, and its correlation with peripheral arterial disease (PAD) has been investigated.
However, it is unclear whether ApoE is associated with PAD in Chinese type 2 diabetes mellitus (T2DM) patients.
Therefore, our study is aimed at investigating the relationship between the ApoE gene polymorphism and PAD in Chinese T2DM patients.
Methods.
A total of 192 T2DM patients were divided into two groups: T2DM and T2DM with PAD.
The clinical and biochemical parameters were obtained.
Polymerase chain reaction was used to identify the genotypes of ApoE.
The multivariable logistic regression analysis was used to identify the possible risk factor for PAD.
Results.
There were no significant differences in the genotype and allele frequencies of ApoE between the T2DM and T2DM with PAD groups.
However, the T2DM with PAD group tended to have more ε4/ε3 genotypes (21.5% vs.
11.3%) than the T2DM group.
The multivariate logistic regression showed that smoking, age, disease duration, TG, LDL, and HbA1c were risk factors for PAD.
Conclusions.
These results demonstrated that there was no evidence of a relationship between ApoE and PAD.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Hu, Yujing& Ling, Tinghuan& Yu, Min& Bai, Yang& Feng, Tongbao& Zhang, Ping…[et al.]. 2020. Apolipoprotein E Gene Polymorphism, Glycated Hemoglobin, and Peripheral Arterial Disease Risk in Chinese Type 2 Diabetic Patients. Disease Markers،Vol. 2020, no. 2020, pp.1-6.
https://search.emarefa.net/detail/BIM-1153910
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Hu, Yujing…[et al.]. Apolipoprotein E Gene Polymorphism, Glycated Hemoglobin, and Peripheral Arterial Disease Risk in Chinese Type 2 Diabetic Patients. Disease Markers No. 2020 (2020), pp.1-6.
https://search.emarefa.net/detail/BIM-1153910
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Hu, Yujing& Ling, Tinghuan& Yu, Min& Bai, Yang& Feng, Tongbao& Zhang, Ping…[et al.]. Apolipoprotein E Gene Polymorphism, Glycated Hemoglobin, and Peripheral Arterial Disease Risk in Chinese Type 2 Diabetic Patients. Disease Markers. 2020. Vol. 2020, no. 2020, pp.1-6.
https://search.emarefa.net/detail/BIM-1153910
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1153910
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر