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Effects of Achyrocline satureioides Inflorescence Extracts against Pathogenic Intestinal Bacteria: Chemical Characterization, In Vitro Tests, and In Vivo Evaluation
المؤلفون المشاركون
Gelain, Daniel Pens
Brandelli, Adriano
Bassani, Valquíria Linck
Moresco, Karla Suzana
Silveira, Alexandre Kleber
Oliveria, Rafael R.
Borges, Adriana Giongo
Grun, Lucas
Barbé-Tuana, Florencia
Zmozinski, Ariane
Vale, Maria Goretti Rodrigues
Corrêa, Ana Paula Folmer
Zeidán-Chuliá, Fares
Fonseca Moreira, José Cláudio
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2017-09-07
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
Three Achyrocline satureioides (AS) inflorescences extracts were characterized: (i) a freeze-dried extract prepared from the aqueous extractive solution and (ii) a freeze-dried and (iii) a spray-dried extract prepared from hydroethanol extractive solution (80% ethanol).
The chemical profile, antioxidant potential, and antimicrobial activity against intestinal pathogenic bacteria of AS extracts were evaluated.
In vitro antioxidant activity was determined by the total reactive antioxidant potential (TRAP) assay.
In vivo analysis and characterization of intestinal microbiota were performed in male Wistar rats (saline versus treated animals with AS dried extracts) by high-throughput sequencing analysis: metabarcoding.
Antimicrobial activity was tested in vitro by the disc diffusion tests.
Moisture content of the extracts ranged from 10 to 15% and 5.7 to 17 mg kg−1 of fluorine.
AS exhibited antioxidant activity, especially in its freeze-dried form which also exhibited a wide spectrum of antimicrobial activity against intestinal pathogenic bacteria greater than those observed by the antibiotic, amoxicillin, when tested against Bacillus cereus and Staphylococcus aureus.
Antioxidant and antimicrobial activities of AS extracts seemed to be positively correlated with the present amount of flavonoids.
These findings suggest a potential use of AS as a coadjuvant agent for treating bacterial-induced intestinal diseases with high rates of antibiotic resistance.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Moresco, Karla Suzana& Silveira, Alexandre Kleber& Zeidán-Chuliá, Fares& Corrêa, Ana Paula Folmer& Oliveria, Rafael R.& Borges, Adriana Giongo…[et al.]. 2017. Effects of Achyrocline satureioides Inflorescence Extracts against Pathogenic Intestinal Bacteria: Chemical Characterization, In Vitro Tests, and In Vivo Evaluation. Evidence-Based Complementary and Alternative Medicine،Vol. 2017, no. 2017, pp.1-10.
https://search.emarefa.net/detail/BIM-1153913
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Moresco, Karla Suzana…[et al.]. Effects of Achyrocline satureioides Inflorescence Extracts against Pathogenic Intestinal Bacteria: Chemical Characterization, In Vitro Tests, and In Vivo Evaluation. Evidence-Based Complementary and Alternative Medicine No. 2017 (2017), pp.1-10.
https://search.emarefa.net/detail/BIM-1153913
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Moresco, Karla Suzana& Silveira, Alexandre Kleber& Zeidán-Chuliá, Fares& Corrêa, Ana Paula Folmer& Oliveria, Rafael R.& Borges, Adriana Giongo…[et al.]. Effects of Achyrocline satureioides Inflorescence Extracts against Pathogenic Intestinal Bacteria: Chemical Characterization, In Vitro Tests, and In Vivo Evaluation. Evidence-Based Complementary and Alternative Medicine. 2017. Vol. 2017, no. 2017, pp.1-10.
https://search.emarefa.net/detail/BIM-1153913
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1153913
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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