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Effects of Electroacupuncture on Methamphetamine-Induced Behavioral Changes in Mice
المؤلفون المشاركون
Chiang, Yao-Chang
Ho, Tsung-Jung
Lee, Chiang-Wen
Lu, Zi-Yun
Tsai, Ming-Horng
Ho, Ing-Kang
Huang, Chieh-Liang
Lane, Hsien-Yuan
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-11، 11ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2017-03-16
دولة النشر
مصر
عدد الصفحات
11
التخصصات الرئيسية
الملخص EN
Methamphetamine (METH) is a major drug of abuse worldwide, and no efficient therapeutic strategies for treating METH addiction are currently available.
Continuous METH use can cause behavioral upregulation or psychosis.
The dopaminergic pathways, particularly the neural circuitry from the ventral tegmental area to the nucleus accumbens (NAc), have a critical role in this behavioral stage.
Acupuncture has been used for treating diseases in China for more than 2000 years.
According to a World Health Organization report, acupuncture can be used to treat several functional disorders, including substance abuse.
In addition, acupuncture is effective against opioids addiction.
In this study, we used electroacupuncture (EA) for treating METH-induced behavioral changes and investigated the possible therapeutic mechanism.
Results showed that EA at the unilateral Zhubin (KI9)–Taichong (LR3) significantly reduced METH-induced behavioral sensitization and conditioned place preference.
In addition, both dopamine and tyrosine hydroxylase (TH) levels decreased but monoamine oxidase A (MAO-A) levels increased in the NAc of the METH-treated mice receiving EA compared with those not receiving EA.
EA may be a useful nonpharmacological approach for treating METH-induced behavioral changes, probably because it reduces the METH-induced TH expression and dopamine levels and raises MAO-A expression in the NAc.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Ho, Tsung-Jung& Lee, Chiang-Wen& Lu, Zi-Yun& Lane, Hsien-Yuan& Tsai, Ming-Horng& Ho, Ing-Kang…[et al.]. 2017. Effects of Electroacupuncture on Methamphetamine-Induced Behavioral Changes in Mice. Evidence-Based Complementary and Alternative Medicine،Vol. 2017, no. 2017, pp.1-11.
https://search.emarefa.net/detail/BIM-1154088
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Ho, Tsung-Jung…[et al.]. Effects of Electroacupuncture on Methamphetamine-Induced Behavioral Changes in Mice. Evidence-Based Complementary and Alternative Medicine No. 2017 (2017), pp.1-11.
https://search.emarefa.net/detail/BIM-1154088
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Ho, Tsung-Jung& Lee, Chiang-Wen& Lu, Zi-Yun& Lane, Hsien-Yuan& Tsai, Ming-Horng& Ho, Ing-Kang…[et al.]. Effects of Electroacupuncture on Methamphetamine-Induced Behavioral Changes in Mice. Evidence-Based Complementary and Alternative Medicine. 2017. Vol. 2017, no. 2017, pp.1-11.
https://search.emarefa.net/detail/BIM-1154088
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1154088
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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