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Zanthoxylum heitzii Modulates Ferric Nitrilotriacetate-Dependent Oxidative Alterations in Four Vital Organs: An In Vitro Organoprotective Model
المؤلفون المشاركون
Moukette, Bruno Moukette
Pieme, Anatole Constant
Joël Essogo, Jacques
Tankeu, Francine Nzufo
Nanfack, Pauline
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-11، 11ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2017-08-09
دولة النشر
مصر
عدد الصفحات
11
التخصصات الرئيسية
الملخص EN
Ferric nitrilotriacetate (Fe-NTA) is a highly reactive compound used to induce degenerative disorders through oxidative stress (OS).
Zanthoxylum heitzii (Z.
heitzii) is a spice used as a medicinal plant to treat a variety of illnesses.
This study investigated the ability of extracts from the leaves, fruits, roots, and barks of Z.
Heitzii to inhibit Fe-NTA mediated oxidative damage in rats.
The supernatant of rat liver homogenates was pretreated with the extracts for one hour before the induction of oxidative damage using a solution of Fe-NTA (400 mM).
The activities of superoxide dismutase (SOD), catalase, and peroxidases were measured together with the marker of lipid peroxidation and the level of glutathione.
The pretreated groups showed a significant increase in the activity of SOD, catalase, and peroxidases.
The methanolic extract from the leaves of Z.
heitzii (36.78 ± 3.30) and aqueous extract from the fruits (37.01 ± 2.52) showed the highest activities of SOD in the liver.
The lowest concentration of MDA was found in the liver, and the glutathione was greater in the brain.
Conclusively, these results suggest that Z.
heitzii might be a chemoprotector which may be used in for prevention of distinct types of diseases induced by oxidative stress.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Joël Essogo, Jacques& Moukette, Bruno Moukette& Tankeu, Francine Nzufo& Nanfack, Pauline& Pieme, Anatole Constant. 2017. Zanthoxylum heitzii Modulates Ferric Nitrilotriacetate-Dependent Oxidative Alterations in Four Vital Organs: An In Vitro Organoprotective Model. Evidence-Based Complementary and Alternative Medicine،Vol. 2017, no. 2017, pp.1-11.
https://search.emarefa.net/detail/BIM-1154189
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Joël Essogo, Jacques…[et al.]. Zanthoxylum heitzii Modulates Ferric Nitrilotriacetate-Dependent Oxidative Alterations in Four Vital Organs: An In Vitro Organoprotective Model. Evidence-Based Complementary and Alternative Medicine No. 2017 (2017), pp.1-11.
https://search.emarefa.net/detail/BIM-1154189
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Joël Essogo, Jacques& Moukette, Bruno Moukette& Tankeu, Francine Nzufo& Nanfack, Pauline& Pieme, Anatole Constant. Zanthoxylum heitzii Modulates Ferric Nitrilotriacetate-Dependent Oxidative Alterations in Four Vital Organs: An In Vitro Organoprotective Model. Evidence-Based Complementary and Alternative Medicine. 2017. Vol. 2017, no. 2017, pp.1-11.
https://search.emarefa.net/detail/BIM-1154189
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1154189
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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