Skin Wound Healing Potential and Mechanisms of the Hydroalcoholic Extract of Leaves and Oleoresin of Copaifera langsdorffii Desf. Kuntze in Rats
المؤلفون المشاركون
Bastos, Jairo Kennup
Hussni, Carlos Alberto
Rozza, A. L.
Gushiken, Lucas Fernando Sérgio
Beserra, Fernando Pereira
Vieira, Ana Júlia
Padovani, Carlos Roberto
Lemos, Marivane
Polizello Junior, Maurilio
Silva, Jonas Joaquim Mangabeira da
Nóbrega, Rafael Henrique
Martinez, Emanuel Ricardo Monteiro
Pellizzon, Cláudia Helena
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-16، 16ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2017-08-27
دولة النشر
مصر
عدد الصفحات
16
التخصصات الرئيسية
الملخص EN
The wound healing is a complex process which, sometimes, can be a problem in public health because of the possibility of physical disability or even death.
Due to the lack of a gold standard drug in skin wound treatment and aiming at the discovery of new treatments in skin repair and the mechanisms involved in the process, we used oleoresin (OR) from Copaifera langsdorffii and hydroalcoholic extract of the leaves (EH) to treat rat skin wounds.
For that, male Wistar rats were divided into groups (n=8): Lanette, Collagenase, 10% EH, or 10% OR and, after anesthesia, one wound of 2 cm was made in the back of animals.
The wounds were treated once a day for 3, 7, or 14 days and the wound areas were measured.
The rats were euthanized and skin samples destined to biochemical, molecular, and immunohistochemical analysis.
The results showed a macroscopic retraction of the wounds of 10% EH and 10% OR creams and both treatments showed anti-inflammatory activity.
Molecular and immunohistochemical results demonstrated the activity of Copaifera langsdorffii creams in angiogenesis, reepithelialization, wound retraction, and remodeling mechanisms.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Gushiken, Lucas Fernando Sérgio& Hussni, Carlos Alberto& Bastos, Jairo Kennup& Rozza, A. L.& Beserra, Fernando Pereira& Vieira, Ana Júlia…[et al.]. 2017. Skin Wound Healing Potential and Mechanisms of the Hydroalcoholic Extract of Leaves and Oleoresin of Copaifera langsdorffii Desf. Kuntze in Rats. Evidence-Based Complementary and Alternative Medicine،Vol. 2017, no. 2017, pp.1-16.
https://search.emarefa.net/detail/BIM-1154370
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Gushiken, Lucas Fernando Sérgio…[et al.]. Skin Wound Healing Potential and Mechanisms of the Hydroalcoholic Extract of Leaves and Oleoresin of Copaifera langsdorffii Desf. Kuntze in Rats. Evidence-Based Complementary and Alternative Medicine No. 2017 (2017), pp.1-16.
https://search.emarefa.net/detail/BIM-1154370
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Gushiken, Lucas Fernando Sérgio& Hussni, Carlos Alberto& Bastos, Jairo Kennup& Rozza, A. L.& Beserra, Fernando Pereira& Vieira, Ana Júlia…[et al.]. Skin Wound Healing Potential and Mechanisms of the Hydroalcoholic Extract of Leaves and Oleoresin of Copaifera langsdorffii Desf. Kuntze in Rats. Evidence-Based Complementary and Alternative Medicine. 2017. Vol. 2017, no. 2017, pp.1-16.
https://search.emarefa.net/detail/BIM-1154370
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1154370
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر