The Effect of a Hydrolyzed Polysaccharide Dietary Supplement on Biomarkers in Adults with Nonalcoholic Fatty Liver Disease
المؤلفون المشاركون
Mendez, A. J.
Lewis, John E.
Atlas, Steven E.
Higuera, Oscar L.
Fiallo, Andrea
Rasul, Ammar
Farooqi, Ashar
Kromo, Olga
Lantigua, Laura A.
Tiozzo, Eduard
Woolger, Judi M.
Goldberg, Sharon
Rodriguez, Allan E.
Konefal, Janet
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-05-03
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
The primary objective of the study was to evaluate the effect of a hydrolyzed polysaccharide, Rice Bran Arabinoxylan Compound (RBAC), on biomarkers in adults with nonalcoholic fatty liver disease (NAFLD).
A 90-day randomized double-blind placebo-controlled trial examined the effect of RBAC on complete blood count, liver enzymes, lipids, oxidative stress markers, cytokines, and growth factors.
Twenty-three adults with NAFLD were enrolled and randomly assigned to one of the two study conditions (n=12 RBAC and n=11 placebo) and consumed 1 gram/day of either compound for 90 days.
Subjects were assessed at baseline and 45 and 90 days.
No adverse effects were reported.
Alkaline phosphatase significantly decreased (−3.1%; SD=19.9; F[1,19]=5.1, p=0.03) in the RBAC group compared to the placebo group.
The percentages of monocytes (17.9%; SD=18.3; F[1,19]=5.9, p=0.02) and eosinophils (30.6%; SD=30.5; F[1,19]=12.3, p<0.01) increased in the RBAC group.
IFN-γ (156%; SD=131.8; F[1,19]=4.2, p=0.06) and IL-18 (29.1%; SD=64; F[1,19]=5.3, p=0.03) increased in the RBAC group compared to the placebo group.
Other improvements were noted for platelets, neutrophils, neutrophil-lymphocyte ratio, γ-glutamyl transferase, and 4-hydroxynonenal.
RBAC had beneficial effects on several biomarkers that adds to the known immunomodulatory activities of RBAC, which may be promising for people with NAFLD.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Lewis, John E.& Atlas, Steven E.& Higuera, Oscar L.& Fiallo, Andrea& Rasul, Ammar& Farooqi, Ashar…[et al.]. 2018. The Effect of a Hydrolyzed Polysaccharide Dietary Supplement on Biomarkers in Adults with Nonalcoholic Fatty Liver Disease. Evidence-Based Complementary and Alternative Medicine،Vol. 2018, no. 2018, pp.1-10.
https://search.emarefa.net/detail/BIM-1154466
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Lewis, John E.…[et al.]. The Effect of a Hydrolyzed Polysaccharide Dietary Supplement on Biomarkers in Adults with Nonalcoholic Fatty Liver Disease. Evidence-Based Complementary and Alternative Medicine No. 2018 (2018), pp.1-10.
https://search.emarefa.net/detail/BIM-1154466
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Lewis, John E.& Atlas, Steven E.& Higuera, Oscar L.& Fiallo, Andrea& Rasul, Ammar& Farooqi, Ashar…[et al.]. The Effect of a Hydrolyzed Polysaccharide Dietary Supplement on Biomarkers in Adults with Nonalcoholic Fatty Liver Disease. Evidence-Based Complementary and Alternative Medicine. 2018. Vol. 2018, no. 2018, pp.1-10.
https://search.emarefa.net/detail/BIM-1154466
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1154466
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر