Antiproliferative and Antibacterial Activities of Cirsium scabrum from Tunisia
المؤلفون المشاركون
Sahpaz, Sevser
Quetin-Leclercq, Joëlle
Sahli, Ramla
Dufloer, Cédric
Beaufay, Claire
Bero, Joanne
Ksouri, Riadh
Roumy, Vincent
Rivière, Céline
Neut, Christel
Hennebelle, Thierry
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2017-07-12
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Several Cirsium species are known for their uses in traditional medicine and consequently are studied for their phytochemical content and their biological activities.
In the framework of a previous study conducted on eight extremophile plants from Tunisia, we highlighted that the crude methanolic extract of C.
scabrum, a not investigated thistle, showed moderate but quite selective cytotoxic activity against the cancerous cell line J774 compared to the noncancerous cell line WI38 (IC50 = 11.53 μg/ml on J774, IC50 = 29.89 µg/ml on WI38, and selectivity index = 2.6).
In the current study, the partitions of the leaves of C.
scabrum were analyzed for their antiproliferative activity on the same cell lines.
From the most active petroleum ether partition, we isolated four triterpenoids including lupeol, taraxasterol acetate, and a (1 : 1) mixture of 25-hydroperoxycycloart-23-en-3β-ol and 24-hydroperoxycycloart-25-en-3β-ol.
These two cycloartane-type triterpenoids are mostly responsible for this cytotoxic activity.
On the other hand, the antimicrobial potential of this plant was also evaluated against 36 microorganisms.
The moderate antibacterial activity against 6 Staphylococcus aureus and 2 Dermabacter hominis strains is mainly attributed to the butanol partition whose major compounds are glycosides of flavones.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Sahli, Ramla& Rivière, Céline& Dufloer, Cédric& Beaufay, Claire& Neut, Christel& Bero, Joanne…[et al.]. 2017. Antiproliferative and Antibacterial Activities of Cirsium scabrum from Tunisia. Evidence-Based Complementary and Alternative Medicine،Vol. 2017, no. 2017, pp.1-9.
https://search.emarefa.net/detail/BIM-1154486
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Sahli, Ramla…[et al.]. Antiproliferative and Antibacterial Activities of Cirsium scabrum from Tunisia. Evidence-Based Complementary and Alternative Medicine No. 2017 (2017), pp.1-9.
https://search.emarefa.net/detail/BIM-1154486
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Sahli, Ramla& Rivière, Céline& Dufloer, Cédric& Beaufay, Claire& Neut, Christel& Bero, Joanne…[et al.]. Antiproliferative and Antibacterial Activities of Cirsium scabrum from Tunisia. Evidence-Based Complementary and Alternative Medicine. 2017. Vol. 2017, no. 2017, pp.1-9.
https://search.emarefa.net/detail/BIM-1154486
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1154486
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر