Regulating the Balance of Th17Treg via Electroacupuncture and Moxibustion: An Ulcerative Colitis Mice Model Based Study
المؤلفون المشاركون
Yang, Ming-Xiao
Wu, Qiaofeng
Wang, Xiang
Yu, Shu-guang
Zhuang, Zhiqi
Sun, Jungang
Zhang, Hejiaozi
Wang, Chengyulin
Chang, Shyang
Geng, Yu
Yang, Hui
Xie, Lushuang
Huang, Biao
Zhao, Na
Zhou, Wei
Cheng, Xinhui
Cai, Bei
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-13، 13ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2017-12-17
دولة النشر
مصر
عدد الصفحات
13
التخصصات الرئيسية
الملخص EN
Aim.
To investigate the relationship between the effects of electroacupuncture/moxibustion and the balance of Th17/Treg in treating ulcerative colitis (UC) and to preliminary compare the effects of the above two methods.
Methods.
DSS-induced UC mice were treated by electroacupuncture and moxibustion.
Disease activity index (DAI) was scored; intestinal pathological structure and ultrastructure were observed.
The levels of IL-2, IL-6, IL-10, IL-17A, IL-17F, and TGF-β in plasma were measured by ELISA.
The percentages of Treg and Th17 in spleen lymphocytes were analyzed by flow cytometry.
Also, the expressions of TLR2, TLR4, RORγt, and FOXP3 in the distal colon were detected by immunohistochemistry or western blot.
Results.
Both electroacupuncture and moxibustion can relieve UC.
These effects are further supported by ELISA results.
In addition, the ratio of Treg and Th17 in spleen lymphocytes and the expression of TLR2 and TLR4 are significantly improved.
Also, the expression of RORγt and FOXP3 in distal colon were improved.
Besides, the effect of moxibustion is better than that of electroacupuncture on TLR2, TLR4, and FOXP3 expression (P<0.05).
Conclusion.
Both electroacupuncture and moxibustion may ameliorate UC by regulating the balance of Th17/Treg.
Whether moxibustion has better efficacy than electroacupuncture needs further study.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Sun, Jungang& Zhang, Hejiaozi& Wang, Chengyulin& Yang, Ming-Xiao& Chang, Shyang& Geng, Yu…[et al.]. 2017. Regulating the Balance of Th17Treg via Electroacupuncture and Moxibustion: An Ulcerative Colitis Mice Model Based Study. Evidence-Based Complementary and Alternative Medicine،Vol. 2017, no. 2017, pp.1-13.
https://search.emarefa.net/detail/BIM-1154500
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Sun, Jungang…[et al.]. Regulating the Balance of Th17Treg via Electroacupuncture and Moxibustion: An Ulcerative Colitis Mice Model Based Study. Evidence-Based Complementary and Alternative Medicine No. 2017 (2017), pp.1-13.
https://search.emarefa.net/detail/BIM-1154500
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Sun, Jungang& Zhang, Hejiaozi& Wang, Chengyulin& Yang, Ming-Xiao& Chang, Shyang& Geng, Yu…[et al.]. Regulating the Balance of Th17Treg via Electroacupuncture and Moxibustion: An Ulcerative Colitis Mice Model Based Study. Evidence-Based Complementary and Alternative Medicine. 2017. Vol. 2017, no. 2017, pp.1-13.
https://search.emarefa.net/detail/BIM-1154500
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1154500
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر