Optimal Dose of Epidural Dexmedetomidine Added to Ropivacaine for Epidural Labor Analgesia: A Pilot Study
المؤلفون المشاركون
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-4، 4ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2017-06-01
دولة النشر
مصر
عدد الصفحات
4
التخصصات الرئيسية
الملخص EN
Background.
Dexmedetomidine combined with local anesthetics can decrease the concentration of epidural ropivacaine.
However, the optimal dose of epidural dexmedetomidine combined with ropivacaine for labor analgesia is still uncertain.
This study investigated the effect of adding different dose of epidural dexmedetomidine to ropivacaine during epidural labor analgesia.
Methods.
One hundred women were randomly assigned to one of the four groups (Groups A, B, C, and D received 0.25, 0.5, 0.75, and 1 μg/ml of dexmedetomidine plus 0.1% ropivacaine, resp.).
The onset of epidural anesthesia and stages of labor were studied, and pain was assessed using a visual analogue scale (VAS).
Hemodynamic parameters and fetal heart rate were monitored.
Apgar scores and umbilical artery pH were recorded.
The side effects, if any, were recorded also.
Results.
The addition of 0.25, 0.5, and 0.75 μg/ml of dexmedetomidine to 0.1% ropivacaine provided safe and effective analgesia, but 1 μg/ml of dexmedetomidine resulted in increasing incidence of motor block.
The hemodynamic parameters were similar between groups (P>0.05).
Side effects in Group D were significantly higher than those in the other three groups (P<0.05).
Conclusions.
When dexmedetomidine is combined with 0.1% ropivacaine, the optimal concentration of dexmedetomidine is 0.5 μg/ml for epidural labor analgesia (this trial is registered with ChiCTR-OPC-16008548).
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Wangping, Zhang& Ming, Ren. 2017. Optimal Dose of Epidural Dexmedetomidine Added to Ropivacaine for Epidural Labor Analgesia: A Pilot Study. Evidence-Based Complementary and Alternative Medicine،Vol. 2017, no. 2017, pp.1-4.
https://search.emarefa.net/detail/BIM-1154631
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Wangping, Zhang& Ming, Ren. Optimal Dose of Epidural Dexmedetomidine Added to Ropivacaine for Epidural Labor Analgesia: A Pilot Study. Evidence-Based Complementary and Alternative Medicine No. 2017 (2017), pp.1-4.
https://search.emarefa.net/detail/BIM-1154631
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Wangping, Zhang& Ming, Ren. Optimal Dose of Epidural Dexmedetomidine Added to Ropivacaine for Epidural Labor Analgesia: A Pilot Study. Evidence-Based Complementary and Alternative Medicine. 2017. Vol. 2017, no. 2017, pp.1-4.
https://search.emarefa.net/detail/BIM-1154631
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1154631
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر