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Assessing the Risk Factors for Refractory Eosinophilic Esophagitis in Children and Adults
المؤلفون المشاركون
Incorvaia, Cristoforo
Ridolo, Erminia
Martignago, Irene
Pellicelli, Irene
المصدر
Gastroenterology Research and Practice
العدد
المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2019-01-13
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Background.
Up to one-third of the patients suffering from eosinophilic esophagitis (EoE) present a refractory form, as defined by nonresponsiveness in clinical, endoscopic, or histological assessment after first-line therapy.
Several studies recently investigated which factors can influence the development of this disease, but very few analyzed the factors underlying refractory EoE.
Methods.
Medical charts of patients affected by EoE were retrospectively evaluated.
Phenotyping of patients was conducted according to demographic, clinical, histological, and treatment variables.
Then, patients were divided into responder and nonresponder to therapy and distinguished among children and adults.
Results.
Forty-five children and 35 adult EoE patients were included.
In the pediatric population, female sex (p<0.05) and a higher score of visual analogue scale (VAS) at the follow-up visit (p=0.02) were significantly associated to the risk of refractory EoE.
Among adults, statistical significance was reached for years of follow-up (p=0.001), diagnostic delay (p=0.03), use of antibiotics during infancy (p=0.01), and food allergy (p=0.04).
Conclusions.
Our study highlighted female sex and a higher VAS score at the time of follow-up visits as risk factors for refractory EoE in children, while the risk factors in adults were identified as fewer years of follow-up, greater diagnostic delay, use of antibiotics during infancy, and food allergy.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Ridolo, Erminia& Martignago, Irene& Pellicelli, Irene& Incorvaia, Cristoforo. 2019. Assessing the Risk Factors for Refractory Eosinophilic Esophagitis in Children and Adults. Gastroenterology Research and Practice،Vol. 2019, no. 2019, pp.1-9.
https://search.emarefa.net/detail/BIM-1154826
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Ridolo, Erminia…[et al.]. Assessing the Risk Factors for Refractory Eosinophilic Esophagitis in Children and Adults. Gastroenterology Research and Practice No. 2019 (2019), pp.1-9.
https://search.emarefa.net/detail/BIM-1154826
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Ridolo, Erminia& Martignago, Irene& Pellicelli, Irene& Incorvaia, Cristoforo. Assessing the Risk Factors for Refractory Eosinophilic Esophagitis in Children and Adults. Gastroenterology Research and Practice. 2019. Vol. 2019, no. 2019, pp.1-9.
https://search.emarefa.net/detail/BIM-1154826
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1154826
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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