Garidisan: Improving the Quality of Ulcer Healing in Rats with Ulcerative Colitis
المؤلفون المشاركون
Wang, Lin
Liu, Wei-Zhi
Pei, Ling-Yan
Ke, Yu-Shi
Cui, Jian
Li, Shu-Chun
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-12، 12ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2017-08-08
دولة النشر
مصر
عدد الصفحات
12
التخصصات الرئيسية
الملخص EN
Garidisan, commonly used in Mongolia to treat ulcerative colitis (UC), contains wild poppy and Artemisia frigida Willd.
Clinical evidence shows that Garidisan can effectively treat UC and that recurrence is low.
Thus, we evaluated the effects of Garidisan on ulcer healing quality and the regulation of immune balance in rats with experimental UC.
UC was induced by immunization with TNBS and Garidisan significantly reduced DAI, CMDI, and HS.
H&E staining, SEM, and VG staining showed that Garidisan repaired damaged intestinal mucosa and significantly reduced expression of ICAM-1 and CD105 in regenerated tissues of UC rats.
Collagen fibers were significantly fewer as well after treatment.
Garidisan elevated EGF, VEGF, bFGF, VEGFR2, and FGFR1 of UC rats, reduced CD3+CD4+/CD3+CD8+ T cell ratios, and increased CD4+Th1/CD4+Th2 cell ratios and IFN-r/IL-4 ratios in peripheral blood of UC rats.
In conclusion, Garidisan promoted tissue maturation of regenerated tissues by regulating the immune balance and improved functional maturity of regenerated tissues by reducing collagen formation, promoting maturation of new blood vessels, and increasing expression of growth factors and their receptors.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Wang, Lin& Liu, Wei-Zhi& Pei, Ling-Yan& Ke, Yu-Shi& Cui, Jian& Li, Shu-Chun. 2017. Garidisan: Improving the Quality of Ulcer Healing in Rats with Ulcerative Colitis. Evidence-Based Complementary and Alternative Medicine،Vol. 2017, no. 2017, pp.1-12.
https://search.emarefa.net/detail/BIM-1154831
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Wang, Lin…[et al.]. Garidisan: Improving the Quality of Ulcer Healing in Rats with Ulcerative Colitis. Evidence-Based Complementary and Alternative Medicine No. 2017 (2017), pp.1-12.
https://search.emarefa.net/detail/BIM-1154831
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Wang, Lin& Liu, Wei-Zhi& Pei, Ling-Yan& Ke, Yu-Shi& Cui, Jian& Li, Shu-Chun. Garidisan: Improving the Quality of Ulcer Healing in Rats with Ulcerative Colitis. Evidence-Based Complementary and Alternative Medicine. 2017. Vol. 2017, no. 2017, pp.1-12.
https://search.emarefa.net/detail/BIM-1154831
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1154831
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر