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Efficacy of Propolis on the Denture Stomatitis Treatment in Older Adults: A Multicentric Randomized Trial
المؤلفون المشاركون
Berretta, Andresa Aparecida
Martins, Vicente P.
de Campos, Tatiana Amabile
Pina, Gisela de M. S.
Lia, Erica N.
Torres, Elina C.
Buszinski, Andrei F. M.
Coelho, Eduardo Barbosa
Rodrigues, Andresa Piacezzi Nascimento
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2017-03-15
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Our hypothesis tested the efficacy and safety of a mucoadhesive oral gel formulation of Brazilian propolis extract compared to miconazole oral gel for the treatment of denture stomatitis due to Candida spp.
infection in older adults.
Forty patients were randomly allocated in a noninferiority clinical trial into two groups.
The control group (MIC) received 20 mg/g miconazole oral gel and the study group (PROP) received mucoadhesive formulation containing standardized extract of 2% (20 mg/g) propolis (EPP-AF®) during 14 days.
Patients were examined on days 1, 7, and 14.
The Newton’s score was used to classify the severity of denture stomatitis.
The colony forming unity count (CFU/mL) was quantified and identified (CHROMagar Candida®) before and after the treatment.
Baseline characteristics did not differ between groups.
Both treatments reduced Newton’s score (P<0.0001), indicating a clinical improvement of the symptoms of candidiasis with a clinical cure rate of 70%.
The microbiological cure with significant reduction in fungal burden on T14 was 70% in the miconazole group and 25% in the EPP-AF group.
The EPP-AF appears to be noninferior to miconazole considering the clinical cure rate and could be recommended as an alternative treatment in older patients.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Pina, Gisela de M. S.& Lia, Erica N.& Berretta, Andresa Aparecida& Rodrigues, Andresa Piacezzi Nascimento& Torres, Elina C.& Buszinski, Andrei F. M.…[et al.]. 2017. Efficacy of Propolis on the Denture Stomatitis Treatment in Older Adults: A Multicentric Randomized Trial. Evidence-Based Complementary and Alternative Medicine،Vol. 2017, no. 2017, pp.1-9.
https://search.emarefa.net/detail/BIM-1154870
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Pina, Gisela de M. S.…[et al.]. Efficacy of Propolis on the Denture Stomatitis Treatment in Older Adults: A Multicentric Randomized Trial. Evidence-Based Complementary and Alternative Medicine No. 2017 (2017), pp.1-9.
https://search.emarefa.net/detail/BIM-1154870
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Pina, Gisela de M. S.& Lia, Erica N.& Berretta, Andresa Aparecida& Rodrigues, Andresa Piacezzi Nascimento& Torres, Elina C.& Buszinski, Andrei F. M.…[et al.]. Efficacy of Propolis on the Denture Stomatitis Treatment in Older Adults: A Multicentric Randomized Trial. Evidence-Based Complementary and Alternative Medicine. 2017. Vol. 2017, no. 2017, pp.1-9.
https://search.emarefa.net/detail/BIM-1154870
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1154870
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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