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Comparison of Polyethylene Glycol versus Lactulose Oral Solution for Bowel Preparation prior to Colonoscopy
المؤلفون المشاركون
Xiao, Qiansong
Chen, Dongfeng
Guo, Yan
Li, Chun-Xia
Zhu, Yang-Jie
Zhu, Jian-Ru
Lan, Chun-Hui
المصدر
Gastroenterology Research and Practice
العدد
المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2019-04-11
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Objective.
This study was conducted to compare a lactulose oral solution with a polyethylene glycol (PEG) formulation for colonoscopy preparation using the following metrics: quality of cleansing, colonoscopy outcomes, patient/physician satisfaction, and patient tolerability.
Methods.
The enrolled patients were randomly divided into two groups and received a single 2 L dose of either PEG (PEG group) or lactulose (Lac group).
The Boston Bowel Preparation Scale (BBPS) was used for assessing the cleansing quality of the bowel preparations.
Patient tolerability and adverse events were obtained through the completion of questionnaires.
Results.
The lactulose oral solution showed superior bowel cleansing compared to PEG, as evidenced by higher BBPS scores in the Lac group for all segments of the colon (P<0.05).
The detection rates of polyps and intestinal lesions in the Lac group (30.68% and 36.36%, respectively) were significantly higher than those in the PEG group (12.50% vs.
13.63%, respectively).
For the degree of satisfaction, the Lac group had significantly higher scores compared to the PEG group, as evaluated by both the patients and endoscopist.
PEG was associated with an increased incidence of nausea.
There were no statistical differences between the groups in terms of vomiting, abdominal pain or fullness, dizziness, unfavorable palatability, dry mouth, palpitation, tinnitus, and tongue numbness.
Conclusion.
A single 2 L dose of a lactulose oral solution had higher efficacy, improved tolerability, and acceptable safety for bowel preparation when compared to the same volume of PEG.
Thus, a lactulose oral solution may be a potential bowel-cleansing option for colonoscopy preparation.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Li, Chun-Xia& Guo, Yan& Zhu, Yang-Jie& Zhu, Jian-Ru& Xiao, Qiansong& Chen, Dongfeng…[et al.]. 2019. Comparison of Polyethylene Glycol versus Lactulose Oral Solution for Bowel Preparation prior to Colonoscopy. Gastroenterology Research and Practice،Vol. 2019, no. 2019, pp.1-6.
https://search.emarefa.net/detail/BIM-1154931
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Li, Chun-Xia…[et al.]. Comparison of Polyethylene Glycol versus Lactulose Oral Solution for Bowel Preparation prior to Colonoscopy. Gastroenterology Research and Practice No. 2019 (2019), pp.1-6.
https://search.emarefa.net/detail/BIM-1154931
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Li, Chun-Xia& Guo, Yan& Zhu, Yang-Jie& Zhu, Jian-Ru& Xiao, Qiansong& Chen, Dongfeng…[et al.]. Comparison of Polyethylene Glycol versus Lactulose Oral Solution for Bowel Preparation prior to Colonoscopy. Gastroenterology Research and Practice. 2019. Vol. 2019, no. 2019, pp.1-6.
https://search.emarefa.net/detail/BIM-1154931
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1154931
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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