![](/images/graphics-bg.png)
Psychotropic Effects of an Alcoholic Extract from the Leaves of Albizia zygia (Leguminosae-Mimosoideae)
المؤلفون المشاركون
Adjei, Samuel
Amoateng, Patrick
Osei-Safo, Dorcas
Kukuia, Kennedy Kwami Edem
Akure, Obed Awintuma
Agbemelo-Tsomafo, Constance
Adu-Poku, Shirley Nyarko
Agyeman-Badu, Kenneth Yaw
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-12، 12ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2017-10-03
دولة النشر
مصر
عدد الصفحات
12
التخصصات الرئيسية
الملخص EN
Background.
Albizia zygia is used in Ghanaian traditional medicine for the management of mental disorders.
The present study tested the hypothesis that an extract of the leaves of Albizia zygia (AZE) may possess antipsychotic and antidepressant properties.
Method.
The novelty- and apomorphine-induced locomotor and rearing behaviours of AZE in mice were explored in an open-field observational test system.
The effects of AZE in apomorphine-induced cage climbing test, extract-induced catalepsy, and haloperidol-induced catalepsy on mice were also investigated.
Lastly, the forced swimming and tail suspension tests in mice were employed to screen the possible antidepressant effects of AZE.
Results.
AZE (100–3000 mg/kg) showed signs of central nervous system (CNS) depression under observation, with no lethality, 24 h after treatment in mice.
AZE (100–1000 mg/kg) produced a significant decrease in the frequency of novelty- and apomorphine-induced locomotor activities in mice.
The extract also significantly decreased the frequency and duration of apomorphine-induced climbing activities in mice.
AZE, while failing to produce any cataleptic event in naïve mice, significantly enhanced haloperidol-induced catalepsy at a dose of 1000 mg/kg.
However, AZE did not produce any significant antidepressant effects in the test models employed.
Conclusion.
The extract of Albizia zygia exhibited an antipsychotic-like activity in mice.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Amoateng, Patrick& Osei-Safo, Dorcas& Kukuia, Kennedy Kwami Edem& Adjei, Samuel& Akure, Obed Awintuma& Agbemelo-Tsomafo, Constance…[et al.]. 2017. Psychotropic Effects of an Alcoholic Extract from the Leaves of Albizia zygia (Leguminosae-Mimosoideae). Evidence-Based Complementary and Alternative Medicine،Vol. 2017, no. 2017, pp.1-12.
https://search.emarefa.net/detail/BIM-1154970
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Amoateng, Patrick…[et al.]. Psychotropic Effects of an Alcoholic Extract from the Leaves of Albizia zygia (Leguminosae-Mimosoideae). Evidence-Based Complementary and Alternative Medicine No. 2017 (2017), pp.1-12.
https://search.emarefa.net/detail/BIM-1154970
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Amoateng, Patrick& Osei-Safo, Dorcas& Kukuia, Kennedy Kwami Edem& Adjei, Samuel& Akure, Obed Awintuma& Agbemelo-Tsomafo, Constance…[et al.]. Psychotropic Effects of an Alcoholic Extract from the Leaves of Albizia zygia (Leguminosae-Mimosoideae). Evidence-Based Complementary and Alternative Medicine. 2017. Vol. 2017, no. 2017, pp.1-12.
https://search.emarefa.net/detail/BIM-1154970
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1154970
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
![](/images/ebook-kashef.png)
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
![](/images/kashef-image.png)