The Effects of Curcumin on Wound Healing in a Rat Model of Nasal Mucosal Trauma
المؤلفون المشاركون
Kalkan, Yildiray
Tümkaya, Levent
Emiroglu, Gokhan
Ozergin Coskun, Zerrin
Celebi Erdivanli, Ozlem
Terzi, Suat
Özgür, Abdulkadir
Demirci, Munir
Dursun, Engin
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2017-09-05
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
We explored the effects of topical curcumin on the healing of nasal mucosal wounds.
A total of 32 Sprague-Dawley Albino rats were randomized in equal numbers into four groups, and unilateral nasal wounds were created using an interdental brush.
Group 1 (the sham-control group) contained untreated rats with traumatized right-side nasal cavities; Group 2 and 3 rats were similarly traumatized and treated with topical curcumin (5 and 10 mg/mL) dissolved in dimethyl sulfoxide daily for 7 days after trauma; Group 4 rats were treated with topical dimethyl sulfoxide only.
All rats were decapitated on day 15 and the healing sites evaluated by blinded observers in terms of the presence of cellular hyperplasia, goblet cell hypertrophy and degeneration, leucocytic infiltration, ciliary loss and degeneration, edema, and vascular dilation.
On histopathological evaluation, all of cellular hyperplasia, leukocytic infiltration, and edema were significantly reduced in Group 3 compared with Group 1 (p=0.001, p=0.004, and p=0.008, resp.).
Thus, curcumin reduced the inflammatory response and significantly accelerated wound healing.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Emiroglu, Gokhan& Ozergin Coskun, Zerrin& Kalkan, Yildiray& Celebi Erdivanli, Ozlem& Tümkaya, Levent& Terzi, Suat…[et al.]. 2017. The Effects of Curcumin on Wound Healing in a Rat Model of Nasal Mucosal Trauma. Evidence-Based Complementary and Alternative Medicine،Vol. 2017, no. 2017, pp.1-6.
https://search.emarefa.net/detail/BIM-1155006
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Emiroglu, Gokhan…[et al.]. The Effects of Curcumin on Wound Healing in a Rat Model of Nasal Mucosal Trauma. Evidence-Based Complementary and Alternative Medicine No. 2017 (2017), pp.1-6.
https://search.emarefa.net/detail/BIM-1155006
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Emiroglu, Gokhan& Ozergin Coskun, Zerrin& Kalkan, Yildiray& Celebi Erdivanli, Ozlem& Tümkaya, Levent& Terzi, Suat…[et al.]. The Effects of Curcumin on Wound Healing in a Rat Model of Nasal Mucosal Trauma. Evidence-Based Complementary and Alternative Medicine. 2017. Vol. 2017, no. 2017, pp.1-6.
https://search.emarefa.net/detail/BIM-1155006
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1155006
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر