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Safety of Simultaneous Hepatectomy and Splenectomy in the Treatment of Hepatocellular Carcinoma Complicated with Hypersplenism: A Meta-analysis
المؤلفون المشاركون
Liu, Xuefeng
Chen, Zhiqiang
Yu, Meng
Zhou, Wei
Zhi, Xuting
Li, Tao
المصدر
Gastroenterology Research and Practice
العدد
المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-17، 17ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2019-08-14
دولة النشر
مصر
عدد الصفحات
17
التخصصات الرئيسية
الملخص EN
Background.
We conducted this meta-analysis to compare the efficacy and safety of simultaneous hepatectomy and splenectomy (HS) with hepatectomy alone (HA) in patients with hepatocellular carcinoma (HCC) and hypersplenism.
Materials and Methods.
A systematic search was conducted in PubMed, Embase, Cochrane Library, and Wanfang Data through March 1, 2018, with no limits.
Two investigators independently screened all retrieved studies.
The investigators of the original publications were contacted if required information was absent.
All the included studies were managed by EndNote X7.
Quality assessment of the included studies was performed using a modified Newcastle-Ottawa Scale judgment.
Extracted data for each endpoint were analyzed by using STATA 12.0 software.
Results.
Thirteen studies, including a total of 1468 patients, comparing the effects of HS with HA were pooled in this meta-analysis.
Outcomes including postoperative complications, perioperative mortality, intraoperative blood transfusion, and albumin (ALB) content at postoperation day (POD) 7 did not differ significantly between the two groups.
Simultaneous approaches significantly promoted 1-, 3-, and 5-year disease-free survival (DFS) rates and overall survival (OS) rates, prolonged operation time, aggravated intraoperative blood loss, increased white blood cell (WBC) and platelet (PLT) counts at POD 7, and lowered total bilirubin (T-Bil) contents at POD 1 and 7.
Conclusion.
Compared to HA, HS is safer and more effective in ameliorating liver function and improving survival of HCC patients complicated with hypersplenism.
This trial is registered with CRD42018093779.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Liu, Xuefeng& Chen, Zhiqiang& Yu, Meng& Zhou, Wei& Zhi, Xuting& Li, Tao. 2019. Safety of Simultaneous Hepatectomy and Splenectomy in the Treatment of Hepatocellular Carcinoma Complicated with Hypersplenism: A Meta-analysis. Gastroenterology Research and Practice،Vol. 2019, no. 2019, pp.1-17.
https://search.emarefa.net/detail/BIM-1155549
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Liu, Xuefeng…[et al.]. Safety of Simultaneous Hepatectomy and Splenectomy in the Treatment of Hepatocellular Carcinoma Complicated with Hypersplenism: A Meta-analysis. Gastroenterology Research and Practice No. 2019 (2019), pp.1-17.
https://search.emarefa.net/detail/BIM-1155549
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Liu, Xuefeng& Chen, Zhiqiang& Yu, Meng& Zhou, Wei& Zhi, Xuting& Li, Tao. Safety of Simultaneous Hepatectomy and Splenectomy in the Treatment of Hepatocellular Carcinoma Complicated with Hypersplenism: A Meta-analysis. Gastroenterology Research and Practice. 2019. Vol. 2019, no. 2019, pp.1-17.
https://search.emarefa.net/detail/BIM-1155549
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1155549
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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