Investigation into the Individualized Treatment of Traditional Chinese Medicine through a Series of N-of-1 Trials
المؤلفون المشاركون
Zhang, Yuqing
Huang, Haiyin
Ma, Ying
Wu, Yingen
Wang, Zhenwei
Yang, Peilan
Wang, Jie
Zi, Suna
Tang, Jie
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-11، 11ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-02-07
دولة النشر
مصر
عدد الصفحات
11
التخصصات الرئيسية
الملخص EN
Purpose.
To compare the efficacy of individualized herbal decoction with standard decoction for patients with stable bronchiectasis through N-of-1 trials.
Methods.
We conducted a single center N-of-1 trials in 17 patients with stable bronchiectasis.
Each N-of-1 trial contains three cycles.
Each cycle is divided into two 4-week intervention including individualized decoction and fixed decoction (control).
The primary outcome was patient self-reported symptoms scores on a 1–7 point Likert scale.
Secondary outcomes were 24-hour sputum volume and CAT scores.
Results.
Among 14 completed trials, five showed that the individualized decoction was statistically better than the control decoction on symptom scores (P<0.05) but was not clinically significant.
The group data of all the trials showed that individualized decoction was superior to control decoction on symptom scores (2.13±0.58 versus 2.30±0.65, P=0.002, mean difference and 95% CI: 0.18 (0.10, 0.25)), 24 h sputum volume (P=0.009), and CAT scores (9.69±4.89 versus 11.64±5.59, P=0.013, mean difference and 95% CI: 1.95 (1.04, 2.86)) but not clinically significant.
Conclusion.
Optimizing the combined analysis of individual and group data and the improvement of statistical models may make contribution in establishing a method of evaluating clinical efficacy in line with the characteristics of traditional Chinese medicine individual diagnosis and treatment.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Huang, Haiyin& Yang, Peilan& Wang, Jie& Wu, Yingen& Zi, Suna& Tang, Jie…[et al.]. 2018. Investigation into the Individualized Treatment of Traditional Chinese Medicine through a Series of N-of-1 Trials. Evidence-Based Complementary and Alternative Medicine،Vol. 2018, no. 2018, pp.1-11.
https://search.emarefa.net/detail/BIM-1155633
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Huang, Haiyin…[et al.]. Investigation into the Individualized Treatment of Traditional Chinese Medicine through a Series of N-of-1 Trials. Evidence-Based Complementary and Alternative Medicine No. 2018 (2018), pp.1-11.
https://search.emarefa.net/detail/BIM-1155633
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Huang, Haiyin& Yang, Peilan& Wang, Jie& Wu, Yingen& Zi, Suna& Tang, Jie…[et al.]. Investigation into the Individualized Treatment of Traditional Chinese Medicine through a Series of N-of-1 Trials. Evidence-Based Complementary and Alternative Medicine. 2018. Vol. 2018, no. 2018, pp.1-11.
https://search.emarefa.net/detail/BIM-1155633
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1155633
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر