Efficacy and Safety of Aidi Injection Combined with Transcatheter Arterial Chemoembolization on Primary Hepatic Carcinoma: A Systematic Review and Meta-Analysis
المؤلفون المشاركون
Xiao, Ya
Chen, Ruixue
Chen, Weihao
Chen, Liguo
Chen, Xudong
Liang, Qiuer
Cai, Yunfei
Wang, Yurong
Zhang, Yun
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-14، 14ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-07-24
دولة النشر
مصر
عدد الصفحات
14
التخصصات الرئيسية
الملخص EN
Objectives.
To evaluate the efficacy and safety of Aidi injection (ADI) combined with transcatheter arterial chemoembolization (TACE) for primary hepatic carcinoma (PHCC).
Methods.
We conducted a literature search in EMBASE, PubMed, CENTRAL, MEDLINE, CNKI, Wanfang, and VIP databases from the earliest possible year to April 2018.
Randomized controlled trials (RCTs) involving ADI combined with TACE versus TACE alone for patients with PHCC were included.
The Cochrane Risk of Bias tool was applied for quality assessment.
Results.
22 studies involving 1611 participants were included.
The clinical response rate (RR = 1.28, 95% CI: 1.17-1.40; P < 0.00001), KPS score (RR = 1.78, 95% CI: 1.59-2.00; P < 0.00001), survival rate (RR = 1.27, 95% CI: 1.16-1.39; P < 0.00001), immune function (MD = 1.24, 95% CI: 0.98-1.51; P < 0.00001), and adverse effects (RR = 0.62, 95% CI: 0.57-0.68; P < 0.00001) of ADI plus TACE showed significant difference when compared with TACE alone.
Conclusions.
ADI combined with TACE in the treatment of PHCC improved the clinical response rate and safety compared to TACE alone.
However, due to poor methodological quality of many of the included RCTs, more rigorously designed and large-scale RCTs are warranted to examine this beneficial effect in the future.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Chen, Weihao& Wang, Yurong& Liang, Qiuer& Cai, Yunfei& Chen, Xudong& Zhang, Yun…[et al.]. 2018. Efficacy and Safety of Aidi Injection Combined with Transcatheter Arterial Chemoembolization on Primary Hepatic Carcinoma: A Systematic Review and Meta-Analysis. Evidence-Based Complementary and Alternative Medicine،Vol. 2018, no. 2018, pp.1-14.
https://search.emarefa.net/detail/BIM-1155868
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Chen, Weihao…[et al.]. Efficacy and Safety of Aidi Injection Combined with Transcatheter Arterial Chemoembolization on Primary Hepatic Carcinoma: A Systematic Review and Meta-Analysis. Evidence-Based Complementary and Alternative Medicine No. 2018 (2018), pp.1-14.
https://search.emarefa.net/detail/BIM-1155868
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Chen, Weihao& Wang, Yurong& Liang, Qiuer& Cai, Yunfei& Chen, Xudong& Zhang, Yun…[et al.]. Efficacy and Safety of Aidi Injection Combined with Transcatheter Arterial Chemoembolization on Primary Hepatic Carcinoma: A Systematic Review and Meta-Analysis. Evidence-Based Complementary and Alternative Medicine. 2018. Vol. 2018, no. 2018, pp.1-14.
https://search.emarefa.net/detail/BIM-1155868
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1155868
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر