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Exploring Chemical Basis of Toxicity Reduction for Processed Roots of Stellera chamaejasme L. Using Ultraperformance Liquid Chromatography–Triple Quadrupole Tandem Mass Spectrometry
المؤلفون المشاركون
Yang, Wei
Ma, Xiaoli
Wang, Ludi
Wei, Mengmeng
Wang, Shuyao
Wu, Siyang
Kang, Chen
Li, Yingfei
المصدر
International Journal of Analytical Chemistry
العدد
المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2019-03-06
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Some herbal medicines are treated with various processing methods to ensure their safe and effective use.
However, chemical basis of toxicity reducing for most herbal medicines remains unclear.
Stellera chamaejasme L., particularly the root (ruixianglangdu), is toxic.
Thus, ruixianglangdu is commonly processed with vinegar or milk to reduce toxicity.
Here, with help of multiple-ion monitoring (MIM)-based metabolomics, we comprehensively capture chemical information of ruixianglangdu.
Then, 33 differential components between crude drugs and processed products were identified or tentatively characterized by multiple-ion monitoring–information dependent acquiring–enhanced product ion (MIM-IDA-EPI), whose level changed after being processed by vinegar or milk.
It was found that flavonoids especially biflavonones could be the important chemical basis of toxicity reduction for processed ruixianglangdu.
In addition, some coumarins and lignanoids could also play a role in reducing toxicity.
It is believed that MIM-based metabolomics method was valuable for exploring chemical basis of toxicity reduction for processing.
The data is critical to further study the mechanism of toxicity reducing for processed ruixianglangdu.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Yang, Wei& Ma, Xiaoli& Wang, Ludi& Wei, Mengmeng& Wang, Shuyao& Wu, Siyang…[et al.]. 2019. Exploring Chemical Basis of Toxicity Reduction for Processed Roots of Stellera chamaejasme L. Using Ultraperformance Liquid Chromatography–Triple Quadrupole Tandem Mass Spectrometry. International Journal of Analytical Chemistry،Vol. 2019, no. 2019, pp.1-9.
https://search.emarefa.net/detail/BIM-1155895
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Yang, Wei…[et al.]. Exploring Chemical Basis of Toxicity Reduction for Processed Roots of Stellera chamaejasme L. Using Ultraperformance Liquid Chromatography–Triple Quadrupole Tandem Mass Spectrometry. International Journal of Analytical Chemistry No. 2019 (2019), pp.1-9.
https://search.emarefa.net/detail/BIM-1155895
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Yang, Wei& Ma, Xiaoli& Wang, Ludi& Wei, Mengmeng& Wang, Shuyao& Wu, Siyang…[et al.]. Exploring Chemical Basis of Toxicity Reduction for Processed Roots of Stellera chamaejasme L. Using Ultraperformance Liquid Chromatography–Triple Quadrupole Tandem Mass Spectrometry. International Journal of Analytical Chemistry. 2019. Vol. 2019, no. 2019, pp.1-9.
https://search.emarefa.net/detail/BIM-1155895
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1155895
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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