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Immunotoxicological Evaluation of Schinus molle L. (Anacardiaceae) Essential Oil in Lymphocytes and Macrophages
المؤلفون المشاركون
Bolignon, Aline
Machado, Michel Mansur
Duarte, Jonathaline Apollo
Zambrano, Léa Augusta de Bairros
Quintana, Luciane Dias
Rocha, Mariana Balhego
Schmitt, Elizandra Gomes
Anraku de Campos, Marli Matiko
Oliveira, Luís Flávio Souza de
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-10-16
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Schinus molle L.
is used to treat various diseases; however, the literature lacks information regarding its possible immunotoxic effects.
The aim of the study was to investigate the immunotoxic effects of essential oil from leaves of Schinus molle L.
in cultures of human lymphocytes and macrophages.
The cultures were treated with essential oil (EO) of Schinus molle L.
and subsequently subjected to genotoxic analysis (comet assay), mutagenic analysis (micronucleus frequency and chromosomal aberration), and cytotoxic (cell viability) and functional parameters (interleukins secretions).
Our analyses have determined that the essential oil from leaves of Schinus molle L.
presents several compounds with α-pinene being the major compound; in addition, the compound verbenene was firstly identified; genotoxic effects were detected only in macrophages and only at the two highest concentrations tested.
An important finding is that Schinus molle L.
oil causes an activation of the immune system.
This action has its mechanism centered by the cascade nitric oxide-interleukin-10-tumor necrosis factor alpha.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Duarte, Jonathaline Apollo& Zambrano, Léa Augusta de Bairros& Quintana, Luciane Dias& Rocha, Mariana Balhego& Schmitt, Elizandra Gomes& Bolignon, Aline…[et al.]. 2018. Immunotoxicological Evaluation of Schinus molle L. (Anacardiaceae) Essential Oil in Lymphocytes and Macrophages. Evidence-Based Complementary and Alternative Medicine،Vol. 2018, no. 2018, pp.1-9.
https://search.emarefa.net/detail/BIM-1155933
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Duarte, Jonathaline Apollo…[et al.]. Immunotoxicological Evaluation of Schinus molle L. (Anacardiaceae) Essential Oil in Lymphocytes and Macrophages. Evidence-Based Complementary and Alternative Medicine No. 2018 (2018), pp.1-9.
https://search.emarefa.net/detail/BIM-1155933
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Duarte, Jonathaline Apollo& Zambrano, Léa Augusta de Bairros& Quintana, Luciane Dias& Rocha, Mariana Balhego& Schmitt, Elizandra Gomes& Bolignon, Aline…[et al.]. Immunotoxicological Evaluation of Schinus molle L. (Anacardiaceae) Essential Oil in Lymphocytes and Macrophages. Evidence-Based Complementary and Alternative Medicine. 2018. Vol. 2018, no. 2018, pp.1-9.
https://search.emarefa.net/detail/BIM-1155933
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1155933
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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