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Herbal Formula Gegen-Qinlian Decoction for Type 2 Diabetes Mellitus: A Meta-Analysis of Randomized Controlled Trials
المؤلفون المشاركون
Ren, Lin
Cheng, Yanxia
Qin, Feng
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-11، 11ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-10-21
دولة النشر
مصر
عدد الصفحات
11
التخصصات الرئيسية
الملخص EN
Background.
Herbal formula Gegen-Qinlian Decoction (GQD) has been widely used in China for the treatment of type 2 diabetes mellitus (T2DM), but its efficacy and safety are unclear.
Method.
The studies were identified from the PubMed, EMBASE, Cochrane Library, China National Knowledge Infrastructure database, Wanfang database, and VIP database using the keywords “Gegenqinlian” or “Gegen-Qinlian” or “Gegen-Qin-Lian” or “Ge Gen Qin Lian.” Relevant studies were selected according to predefined inclusion and exclusion criteria.
Study selection, data extraction, and validation were carried out by, at least, two reviewers with disagreements being settled by discussion.
Results.
After literature search, a total of 26 randomized controlled trials were included with a total of 2553 patients.
There was evidence that compared with metformin, the combination of GQD and metformin significantly reduced the fasting plasma glucose levels (MD −1.79, 95% CI (−2.31, −1.27), p<0.00001); 2-hour postprandial plasma glucose levels (MD −1.72, 95% CI (−2.12, −1.31), p<0.00001); and glycosylated hemoglobin levels (MD −1.26, 95% CI (−1.80, −0.72), p<0.00001), and no serious side effects were identified.
Conclusion.
These data suggest that GQD may be an effective herbal formula in treating T2DM without serious side effects.
The addition of GQD also enhances the hypoglycemic effects of metformin.
However, the evidence remains weak due to methodological flaws, which may amplify the therapeutic benefit of GQD.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Ren, Lin& Cheng, Yanxia& Qin, Feng. 2020. Herbal Formula Gegen-Qinlian Decoction for Type 2 Diabetes Mellitus: A Meta-Analysis of Randomized Controlled Trials. Evidence-Based Complementary and Alternative Medicine،Vol. 2020, no. 2020, pp.1-11.
https://search.emarefa.net/detail/BIM-1155987
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Ren, Lin…[et al.]. Herbal Formula Gegen-Qinlian Decoction for Type 2 Diabetes Mellitus: A Meta-Analysis of Randomized Controlled Trials. Evidence-Based Complementary and Alternative Medicine No. 2020 (2020), pp.1-11.
https://search.emarefa.net/detail/BIM-1155987
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Ren, Lin& Cheng, Yanxia& Qin, Feng. Herbal Formula Gegen-Qinlian Decoction for Type 2 Diabetes Mellitus: A Meta-Analysis of Randomized Controlled Trials. Evidence-Based Complementary and Alternative Medicine. 2020. Vol. 2020, no. 2020, pp.1-11.
https://search.emarefa.net/detail/BIM-1155987
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1155987
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