In Vivo Antiplasmodial Activity of Two Sahelian Plant Extracts on Plasmodium berghei ANKA Infected NMRI Mice
المؤلفون المشاركون
Bonkian, Léa Nadège
Yerbanga, R. Serge
Koama, Benjamin
Soma, Aboubakar
Cisse, Mamoudou
Valea, Innocent
Tinto, Halidou
Ouedraogo, Jean Bosco
Guigemde, T. Robert
Traore/Coulibaly, Maminata
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-4، 4ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-05-24
دولة النشر
مصر
عدد الصفحات
4
التخصصات الرئيسية
الملخص EN
Up to now, the control of malaria remains a challenge.
The World Health Organization (WHO) recommends the use of artemisinin-based combination therapies (ACTs) for uncomplicated malaria treatment.
Despite this guideline, many people in Burkina Faso use herbal medicine as primary treatment against malaria.
The aim of this study was to assess the in vivo activity of Guiera senegalensis J.
F.
Gmel and Bauhinia rufescens Lam.
leaves extracts against Plasmodium berghei ANKA.
A four-day treatment of leaves decoction of each plant was administrated orally to 7 groups of six NMRI (Naval Medical Research Institute) mice infected with Plasmodium berghei ANKA strain.
The control group received distilled water as treatment while the treated groups each received daily 100, 250, and 500 mg extract/kg body weight.
Thin blood smears were performed on day five and the percentage of reduction of parasitaemia was determined compared to the control.
The percentages of reduction of the parasitaemia at the doses of 100, 250, and 500 mg extract/kg body weight were, respectively, 57.5%, 35.9%, and 44.9% for Guiera senegalensis and 50.6%, 22.2%, and 25.7% for Bauhinia rufescens.
Our findings on antiplasmodial activity of these two plants justify the traditional use by local populations against malaria.
Thus, the isolation of the active compounds from these two plants is suggested for possible antimalarial candidate drugs.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Bonkian, Léa Nadège& Yerbanga, R. Serge& Koama, Benjamin& Soma, Aboubakar& Cisse, Mamoudou& Valea, Innocent…[et al.]. 2018. In Vivo Antiplasmodial Activity of Two Sahelian Plant Extracts on Plasmodium berghei ANKA Infected NMRI Mice. Evidence-Based Complementary and Alternative Medicine،Vol. 2018, no. 2018, pp.1-4.
https://search.emarefa.net/detail/BIM-1156056
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Bonkian, Léa Nadège…[et al.]. In Vivo Antiplasmodial Activity of Two Sahelian Plant Extracts on Plasmodium berghei ANKA Infected NMRI Mice. Evidence-Based Complementary and Alternative Medicine No. 2018 (2018), pp.1-4.
https://search.emarefa.net/detail/BIM-1156056
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Bonkian, Léa Nadège& Yerbanga, R. Serge& Koama, Benjamin& Soma, Aboubakar& Cisse, Mamoudou& Valea, Innocent…[et al.]. In Vivo Antiplasmodial Activity of Two Sahelian Plant Extracts on Plasmodium berghei ANKA Infected NMRI Mice. Evidence-Based Complementary and Alternative Medicine. 2018. Vol. 2018, no. 2018, pp.1-4.
https://search.emarefa.net/detail/BIM-1156056
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1156056
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر