Effects of a Long-Acting Formulation of Octreotide on Patients with Portal Hypertension
المؤلفون المشاركون
Cui, Pei-Jing
Yao, Jing
Zhu, Yin
Zhang, Zheng-Yun
Yang, Jun
المصدر
Gastroenterology Research and Practice
العدد
المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2017-08-10
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Objective.
This study aimed to determine whether the treatment of a long-acting formulation of octreotide (OCT-LAR) exerted a similar effect on improving the prognosis of patients with portal hypertension compared with placement of transjugular intrahepatic portosystemic shunts (TIPSs).
Methods.
A total of 24 patients with portal hypertension who underwent TIPS placement or OCT-LAR treatment from January 2010 to January 2015 were reviewed.
Hemodynamic studies, biological values, live functions, and treatment complications before and during the treatment were evaluated.
Results.
Baseline clinical characteristics were similar between two groups.
Hepatic venous pressure gradient (HVPG) was improved in OCT-LAR groups (15.9 ± 2.4 to 12.8 ± 1.6 mmHg).
Both groups showed a slight decrease in endothelin-1 (ET-1) and urotensin II and a slight increase in oxide metabolite (NOx) concentrations with no significant difference.
Aspartate aminotransferase and alanine aminotransferase increased one week after TIPS placement when they improved in the OCT-LAR treatment group.
The complications of OCT-LAR treatment were minor and transient.
However, one patient who received TIPS placement presented procedure-related complications and required rehospitalization, and 2 patients had developed hepatic encephalopathy during the follow-up period.
Conclusion.
Prolonged administration of OCT-LAR exerted a virtually similar effect on improving hemodynamic parameters and liver function in patients with portal hypertension compared with placement of TIPS, with no apparent serious adverse effects.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Cui, Pei-Jing& Yao, Jing& Zhu, Yin& Zhang, Zheng-Yun& Yang, Jun. 2017. Effects of a Long-Acting Formulation of Octreotide on Patients with Portal Hypertension. Gastroenterology Research and Practice،Vol. 2017, no. 2017, pp.1-6.
https://search.emarefa.net/detail/BIM-1156362
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Cui, Pei-Jing…[et al.]. Effects of a Long-Acting Formulation of Octreotide on Patients with Portal Hypertension. Gastroenterology Research and Practice No. 2017 (2017), pp.1-6.
https://search.emarefa.net/detail/BIM-1156362
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Cui, Pei-Jing& Yao, Jing& Zhu, Yin& Zhang, Zheng-Yun& Yang, Jun. Effects of a Long-Acting Formulation of Octreotide on Patients with Portal Hypertension. Gastroenterology Research and Practice. 2017. Vol. 2017, no. 2017, pp.1-6.
https://search.emarefa.net/detail/BIM-1156362
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1156362
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر