Clinicopathological Features and Prognostic Factors of Colorectal Neuroendocrine Neoplasms
المؤلفون المشاركون
Jiang, Mengjie
Tan, Yinuo
Li, Xiaofen
Fu, Jianfei
Hu, Hanguang
Ye, Xianyun
Cao, Ying
Xu, Jinghong
Yuan, Ying
المصدر
Gastroenterology Research and Practice
العدد
المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2017-01-17
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Background.
Limited research is available regarding colorectal NENs and the prognostic factors remain controversial.
Materials and Methods.
A total of 68 patients with colorectal NENs were studied retrospectively.
Clinical characteristics and prognosis between colonic and rectal NENs were compared.
The Cox regression models were used to evaluate the predictive capacity.
Results.
Of the 68 colorectal NENs patients, 43 (63.2%) had rectal NENs, and 25 (36.8%) had colonic NENs.
Compared with rectal NENs, colonic NENs more frequently exhibited larger tumor size (P<0.0001) and distant metastasis (P<0.0001).
Colonic NENs had a worse prognosis (P=0.027), with 5-year overall survival rates of 66.7% versus 88.1%.
NET, NEC, and MANEC were noted in 61.8%, 23.5%, and 14.7% of patients, respectively.
Multivariate analyses revealed that tumor location was not an independent prognostic factor (P=0.081), but tumor size (P=0.037) and pathological classification (P=0.012) were independent prognostic factors.
Conclusion.
Significant differences exist between colonic and rectal NENs.
Multivariate analysis indicated that tumor size and pathological classification were associated with prognosis.
Tumor location was not an independent factor.
The worse outcome of colonic NENs observed in clinical practice might be due not only to the biological differences, but also to larger tumor size in colonic NENs caused by the delayed diagnosis.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Jiang, Mengjie& Tan, Yinuo& Li, Xiaofen& Fu, Jianfei& Hu, Hanguang& Ye, Xianyun…[et al.]. 2017. Clinicopathological Features and Prognostic Factors of Colorectal Neuroendocrine Neoplasms. Gastroenterology Research and Practice،Vol. 2017, no. 2017, pp.1-9.
https://search.emarefa.net/detail/BIM-1156376
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Jiang, Mengjie…[et al.]. Clinicopathological Features and Prognostic Factors of Colorectal Neuroendocrine Neoplasms. Gastroenterology Research and Practice No. 2017 (2017), pp.1-9.
https://search.emarefa.net/detail/BIM-1156376
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Jiang, Mengjie& Tan, Yinuo& Li, Xiaofen& Fu, Jianfei& Hu, Hanguang& Ye, Xianyun…[et al.]. Clinicopathological Features and Prognostic Factors of Colorectal Neuroendocrine Neoplasms. Gastroenterology Research and Practice. 2017. Vol. 2017, no. 2017, pp.1-9.
https://search.emarefa.net/detail/BIM-1156376
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1156376
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر