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Clostridium difficile in Inflammatory Bowel Disease: A Retrospective Study
المؤلفون المشاركون
Gillespie, William
Marya, Neil
Fahed, Julien
Leslie, Gregory
Patel, Krunal
Cave, David R.
المصدر
Gastroenterology Research and Practice
العدد
المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-5، 5ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2017-10-04
دولة النشر
مصر
عدد الصفحات
5
التخصصات الرئيسية
الملخص EN
Aim.
To investigate the epidemiology and risk factors of Clostridium difficile infections (CDI) in patients with inflammatory bowel disease (IBD).
Methods.
This is a retrospective study of patients diagnosed with IBD.
1006 charts were screened and 654 patients met the inclusion criteria.
Patients were divided into 2 cohorts based on the presence of prior diagnosis of CDI.
Statistical analysis with Pearson’s chi-squared and two-sample t-test was performed.
Results.
The incidence of CDI among IBD patients was 6.7%.
There was equal prevalence of CDI among Crohn’s disease (CD) (n=21, 49%) and ulcerative colitis (UC) (n=22, 51%).
IBD patients acquired CDI at a mean age of 42.7 years, with 56% of infections acquired in the community and only 28% associated with healthcare.
Only 30% of IBD patients with CDI had prior antibiotic use, and 16% had prior steroid use.
IBD patients were significantly more likely to require biologic therapy (57% versus 37%, p<0.01) and have extraintestinal manifestations of IBD (43% versus 28%, p<0.02).
Conclusions.
IBD patients are more susceptible to CDI at a younger age and often lack traditional risk factors.
IBD patients with at least one CDI were more likely to require biologic therapy and had greater rates of extraintestinal manifestations.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Gillespie, William& Marya, Neil& Fahed, Julien& Leslie, Gregory& Patel, Krunal& Cave, David R.. 2017. Clostridium difficile in Inflammatory Bowel Disease: A Retrospective Study. Gastroenterology Research and Practice،Vol. 2017, no. 2017, pp.1-5.
https://search.emarefa.net/detail/BIM-1156411
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Gillespie, William…[et al.]. Clostridium difficile in Inflammatory Bowel Disease: A Retrospective Study. Gastroenterology Research and Practice No. 2017 (2017), pp.1-5.
https://search.emarefa.net/detail/BIM-1156411
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Gillespie, William& Marya, Neil& Fahed, Julien& Leslie, Gregory& Patel, Krunal& Cave, David R.. Clostridium difficile in Inflammatory Bowel Disease: A Retrospective Study. Gastroenterology Research and Practice. 2017. Vol. 2017, no. 2017, pp.1-5.
https://search.emarefa.net/detail/BIM-1156411
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1156411
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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