Antibacterial Effects of Leaf Extract of Nandina domestica and the Underlined Mechanism
المؤلفون المشاركون
Guo, Zhao-Yu
Zhang, Zhuo-Yang
Xiao, Jia-Qi
Qin, Jin-Hong
Zhao, Wei
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-01-18
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Aim.
The study was conducted to investigate the antibacterial and antiasthmatic effects of Nandina domestica leaf extract, to find out its active components, and to assess its safety issue.
Methods.
(1) Solid-phase agar dilution method was used for antibacterial activity test of nandina leaf extract and the change of bacterial morphology after treatment was observed under the transmission microscope; (2) guinea pig model of asthma was used to test the asthma prevention effect of nandina leaf extract; (3) alkaloids and flavones were separated from nandina leaf extract and were further analyzed with HPLC-MS; (4) mice model was used to assessment of the safety issue of nandina leaf extract.
Results.
(1) Nandina leaf extract inhibited the growth of bacteria and destroyed bacterial membrane; (2) nandina leaf extract alleviated animal allergy and asthma; (3) the components reextracted by ethyl acetate were active, in which alkaloids inhibited Gram-positive bacteria and prevented asthma and flavones inhibited Gram-negative bacteria; (4) nandina leaf extract had no toxic effect on mice.
Conclusion.
Nandina leaves inhibit bacterial growth and prevent asthma through alkaloids and flavones, which had integrated function against chronic bronchitis.
This study provided theoretical basement for producing new Chinese medicine against chronic bronchitis.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Guo, Zhao-Yu& Zhang, Zhuo-Yang& Xiao, Jia-Qi& Qin, Jin-Hong& Zhao, Wei. 2018. Antibacterial Effects of Leaf Extract of Nandina domestica and the Underlined Mechanism. Evidence-Based Complementary and Alternative Medicine،Vol. 2018, no. 2018, pp.1-9.
https://search.emarefa.net/detail/BIM-1156498
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Guo, Zhao-Yu…[et al.]. Antibacterial Effects of Leaf Extract of Nandina domestica and the Underlined Mechanism. Evidence-Based Complementary and Alternative Medicine No. 2018 (2018), pp.1-9.
https://search.emarefa.net/detail/BIM-1156498
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Guo, Zhao-Yu& Zhang, Zhuo-Yang& Xiao, Jia-Qi& Qin, Jin-Hong& Zhao, Wei. Antibacterial Effects of Leaf Extract of Nandina domestica and the Underlined Mechanism. Evidence-Based Complementary and Alternative Medicine. 2018. Vol. 2018, no. 2018, pp.1-9.
https://search.emarefa.net/detail/BIM-1156498
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1156498
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر