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Extraction, Characterization, Antioxidant, and Immunostimulatory Activities of Polysaccharides from Hedyotis corymbosa
المؤلفون المشاركون
Lin, Li-mei
Zhao, Ling-jia
Xiong, Su-hui
Xia, Bo-hou
Tang, Jie
Zhang, Zhi-min
Li, Ya-mei
Zheng, Tao
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-11-14
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
In this study, optimization of enzyme-assisted extraction, purification, characterization, and its bioactivities of polysaccharides from Hedyotis corymbosa (HCP) was investigated.
It was found that the optimum extraction conditions were 3% of enzyme concentration (X 1), 30 of liquid-to-solid ratio (X 2), 56°C of extraction temperature (X 3), 200W of ultrasonic power (X 4), 10 min of extraction time (X 5), and 5 of pH value (X 6).
Under optimum conditions, the experimental yield (4.10 ± 0.16%) was closed to the predicted value (4.02%).
The crude HCP was further purified using DEAE-52 and Sephadex G-150 gel column, and a major polysaccharide fraction from HCP, designed as HCP-1a with molecular weight of 33.9 kDa, was obtained.
The HCP and HCP-1a were characterized by chemical analysis, FT-IR, and HPLC.
For antioxidant activities in vitro, HCP possessed strong hydroxyl radical scavenging, DPPH radical scavenging, and Fe2+ chelating activities.
In subsequent immunostimulatory studies, significantly decreased NO, IL-1β, and TNF-α concentrations were observed in both of HCP and HCP-1a treated RAW264.7 cells.
Therefore, this study may indicate some insights into the application of polysaccharides from Hedyotis corymbosa as potential natural antioxidants and immunostimulants.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Lin, Li-mei& Xiong, Su-hui& Zhao, Ling-jia& Tang, Jie& Zhang, Zhi-min& Li, Ya-mei…[et al.]. 2018. Extraction, Characterization, Antioxidant, and Immunostimulatory Activities of Polysaccharides from Hedyotis corymbosa. Evidence-Based Complementary and Alternative Medicine،Vol. 2018, no. 2018, pp.1-10.
https://search.emarefa.net/detail/BIM-1156661
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Lin, Li-mei…[et al.]. Extraction, Characterization, Antioxidant, and Immunostimulatory Activities of Polysaccharides from Hedyotis corymbosa. Evidence-Based Complementary and Alternative Medicine No. 2018 (2018), pp.1-10.
https://search.emarefa.net/detail/BIM-1156661
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Lin, Li-mei& Xiong, Su-hui& Zhao, Ling-jia& Tang, Jie& Zhang, Zhi-min& Li, Ya-mei…[et al.]. Extraction, Characterization, Antioxidant, and Immunostimulatory Activities of Polysaccharides from Hedyotis corymbosa. Evidence-Based Complementary and Alternative Medicine. 2018. Vol. 2018, no. 2018, pp.1-10.
https://search.emarefa.net/detail/BIM-1156661
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1156661
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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