Prevalence of Anemia in Pediatric IBD Patients and Impact on Disease Severity: Results of the Pediatric IBD-Registry CEDATA-GPGE®
المؤلفون المشاركون
Laffolie, Jan de
Laass, Martin W.
Scholz, Dietmar
Zimmer, Klaus-Peter
Buderus, Stephan
M'Koma, Amosy
المصدر
Gastroenterology Research and Practice
العدد
المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2017-12-05
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Aim.
To determine the prevalence of anemia and its association with disease severity in children and adolescents with IBD.
Methods.
CEDATA-GPGE is a registry for pediatric patients with IBD in Germany and Austria from 90 specialized centers.
As markers of disease severity, analysis included patient self-assessment on a Likert scale (1–5; 1 = very good) and physicians’ general assessment (0 = no activity to 4 = severe disease) and the disease indices.
Anemia was defined as hemoglobin concentration below the 3rd percentile.
Results.
Prevalence of anemia was 65.2% in CD and 60.2% in UC.
Anemic CD and UC patients showed significantly worse self-assessment than patients without anemia (average ± standard deviation; CD: 3.0 ± 0.9 versus 2.5 ± 0.9, p<0.0001; UC: 2.9 ± 0.9 versus 2.3 ± 0.9, p<0.0001).
Accordingly, physicians’ general assessment (PGA) was significantly worse in anemic than in nonanemic patients in CD (p<0.0001) and UC (p<0.0001).
PCDAI in anemic CD, p<0.0001, and PUCAI in anemic UC patients, p<0.0001, were significantly higher than in nonanemic patients.
40.0% of anemic CD and 47.8% of anemic UC patients received iron during follow-up.
Conclusion.
Almost 2/3 of pediatric IBD patients are anemic.
Patients’ self-assessment and disease severity as determined by PGA and activity indices are worse in anemic patients.
Contrastingly, only a minority received iron therapy.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Laffolie, Jan de& Laass, Martin W.& Scholz, Dietmar& Zimmer, Klaus-Peter& Buderus, Stephan& M'Koma, Amosy. 2017. Prevalence of Anemia in Pediatric IBD Patients and Impact on Disease Severity: Results of the Pediatric IBD-Registry CEDATA-GPGE®. Gastroenterology Research and Practice،Vol. 2017, no. 2017, pp.1-8.
https://search.emarefa.net/detail/BIM-1156669
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Laffolie, Jan de…[et al.]. Prevalence of Anemia in Pediatric IBD Patients and Impact on Disease Severity: Results of the Pediatric IBD-Registry CEDATA-GPGE®. Gastroenterology Research and Practice No. 2017 (2017), pp.1-8.
https://search.emarefa.net/detail/BIM-1156669
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Laffolie, Jan de& Laass, Martin W.& Scholz, Dietmar& Zimmer, Klaus-Peter& Buderus, Stephan& M'Koma, Amosy. Prevalence of Anemia in Pediatric IBD Patients and Impact on Disease Severity: Results of the Pediatric IBD-Registry CEDATA-GPGE®. Gastroenterology Research and Practice. 2017. Vol. 2017, no. 2017, pp.1-8.
https://search.emarefa.net/detail/BIM-1156669
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1156669
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر