Network Pharmacology-Based Identification of the Mechanisms of Shen-Qi Compound Formula in Treating Diabetes Mellitus
المؤلفون المشاركون
Liu, Ya
Yang, Liangjun
Hu, Zhipeng
Yang, Maoyi
Xie, Chunguang
Gao, Hong
Fu, Xiaoxu
Xie, Hongyan
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-15، 15ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-06-04
دولة النشر
مصر
عدد الصفحات
15
التخصصات الرئيسية
الملخص EN
Aim.
The purpose of this research is to identify the mechanisms of Shen-Qi compound formula (SQC), a traditional Chinese medicine (TCM), for treating diabetes mellitus (DM) using system pharmacology.
Methods.
The active components and therapeutic targets were identified, and these targets were analyzed using gene ontology (GO) enrichment analysis, Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analysis, and protein-protein interaction (PPI) analysis.
Finally, an integrated pathway was constructed to show the mechanisms of SQC.
Results.
A total of 282 active components and 195 targets were identified through a database search.
The component-target network was constructed, and the key components were screened out according to their degree.
Through the GO, PPI, and KEGG analyses, the mechanism network of SQC treating DM was constructed.
Conclusions.
This study shows that the mechanisms of SQC treating DM are related to various pathways and targets.
This study provides a good foundation and basis for further in-depth verification and clinical application.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Hu, Zhipeng& Yang, Maoyi& Yang, Liangjun& Xie, Chunguang& Gao, Hong& Fu, Xiaoxu…[et al.]. 2020. Network Pharmacology-Based Identification of the Mechanisms of Shen-Qi Compound Formula in Treating Diabetes Mellitus. Evidence-Based Complementary and Alternative Medicine،Vol. 2020, no. 2020, pp.1-15.
https://search.emarefa.net/detail/BIM-1156711
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Hu, Zhipeng…[et al.]. Network Pharmacology-Based Identification of the Mechanisms of Shen-Qi Compound Formula in Treating Diabetes Mellitus. Evidence-Based Complementary and Alternative Medicine No. 2020 (2020), pp.1-15.
https://search.emarefa.net/detail/BIM-1156711
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Hu, Zhipeng& Yang, Maoyi& Yang, Liangjun& Xie, Chunguang& Gao, Hong& Fu, Xiaoxu…[et al.]. Network Pharmacology-Based Identification of the Mechanisms of Shen-Qi Compound Formula in Treating Diabetes Mellitus. Evidence-Based Complementary and Alternative Medicine. 2020. Vol. 2020, no. 2020, pp.1-15.
https://search.emarefa.net/detail/BIM-1156711
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1156711
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر