Efficacy and Safety of Bushenjiangya-Optimized Granule for Left Ventricular Diastolic Dysfunction in Hypertensive Patients: A Double-Blind, Randomized, Placebo-Controlled Trial
المؤلفون المشاركون
Cui, Xiaoyun
Gao, Qun
Liu, Jing
Lin, Qian
Lu, Jinjin
Zhou, Kun
Qu, Wenbai
Dong, Fei
Fan, Wen-ying
Li, Pin-hui
Meng, Yan
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-05-19
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Objective.
The study aimed to evaluate the efficacy and safety of Bushenjiangya-optimized (BSJYO) granule on left ventricular diastolic dysfunction (LVDD) in hypertensive (HTN) patients.
Methods.
120 patients diagnosed with HTN plus LVDD were randomly assigned to the BSJYO granule group and placebo group, and all patients received basal western medicine (WM) treatment.
After eight weeks of treatment, we evaluated echocardiography, traditional Chinese medicine (TCM) syndromes, 24-hour ambulatory blood pressure, liver and kidney functions, and adverse events.
Major adverse cardiovascular events (MACEs) were collected at 6-month follow-up.
Results.
Compared with pretreatment, E/Ea (Doppler-derived index of filling pressure and worsening LVDD) significantly decreased significantly after 8 weeks of treatment in the BSJYO granule plus basal WM group (10.52 ± 1.87 vs.
9.49 ± 1.49, P<0.01), alongside reductions in significantly effective response (SER), effective response (ER), and total effective response (TER = SER + ER) in TCM symptom scores (21.59% vs.
71.70%, P<0.01).
There were no differences between treatment groups in kidney and liver function, early adverse events, or MACE.
Conclusion.
BSJYO granule plus basal WM is an effective and safe therapy for HTN patients with LVDD.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Gao, Qun& Cui, Xiaoyun& Dong, Fei& Fan, Wen-ying& Li, Pin-hui& Liu, Jing…[et al.]. 2020. Efficacy and Safety of Bushenjiangya-Optimized Granule for Left Ventricular Diastolic Dysfunction in Hypertensive Patients: A Double-Blind, Randomized, Placebo-Controlled Trial. Evidence-Based Complementary and Alternative Medicine،Vol. 2020, no. 2020, pp.1-6.
https://search.emarefa.net/detail/BIM-1157186
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Gao, Qun…[et al.]. Efficacy and Safety of Bushenjiangya-Optimized Granule for Left Ventricular Diastolic Dysfunction in Hypertensive Patients: A Double-Blind, Randomized, Placebo-Controlled Trial. Evidence-Based Complementary and Alternative Medicine No. 2020 (2020), pp.1-6.
https://search.emarefa.net/detail/BIM-1157186
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Gao, Qun& Cui, Xiaoyun& Dong, Fei& Fan, Wen-ying& Li, Pin-hui& Liu, Jing…[et al.]. Efficacy and Safety of Bushenjiangya-Optimized Granule for Left Ventricular Diastolic Dysfunction in Hypertensive Patients: A Double-Blind, Randomized, Placebo-Controlled Trial. Evidence-Based Complementary and Alternative Medicine. 2020. Vol. 2020, no. 2020, pp.1-6.
https://search.emarefa.net/detail/BIM-1157186
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1157186
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر