Evidence of TCM Theory in Treating the Same Disease with Different Methods: Treatment of Pneumonia with Ephedra sinica and Scutellariae Radix as an Example
المؤلفون المشاركون
Wang, Dandan
Xu, Yan
Sun, Liping
Qi, Wenxiu
Wang, Yanbo
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-23، 23ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-11-28
دولة النشر
مصر
عدد الصفحات
23
التخصصات الرئيسية
الملخص EN
Pneumonia is a serious global health problem and the leading cause of mortality in children.
Antibiotics are the main treatment for bacterial pneumonia, but there are serious drug resistance problems.
Traditional Chinese medicine (TCM) has been used to treat diseases for thousands of years and has a unique theory.
This article takes the treatment of pneumonia with Ephedra sinica as a representative hot medicine and Scutellariae Radix as a representative cold medicine as an example.
We explore and explain the theory of treating the same disease with different TCM treatments.
Using transcriptomics and network pharmacology methods, GO, KEGG enrichment, and PPI network construction were carried out, demonstrating that Ephedra sinica plays a therapeutic role through the NF-κB and apoptosis signaling pathways targeting PLAU, CD40LG, BLC2L1, CASP7, and CXCL8.
The targets of Scutellariae Radix through the IL-17 signaling pathway are MMP9, CXCL8, and MAPK14.
Molecular docking technology was also used to verify the results.
In short, our results provide evidence for the theory of treating the same disease with different treatments, and we also discuss future directions for traditional Chinese medicine.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Sun, Liping& Wang, Dandan& Xu, Yan& Qi, Wenxiu& Wang, Yanbo. 2020. Evidence of TCM Theory in Treating the Same Disease with Different Methods: Treatment of Pneumonia with Ephedra sinica and Scutellariae Radix as an Example. Evidence-Based Complementary and Alternative Medicine،Vol. 2020, no. 2020, pp.1-23.
https://search.emarefa.net/detail/BIM-1158157
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Sun, Liping…[et al.]. Evidence of TCM Theory in Treating the Same Disease with Different Methods: Treatment of Pneumonia with Ephedra sinica and Scutellariae Radix as an Example. Evidence-Based Complementary and Alternative Medicine No. 2020 (2020), pp.1-23.
https://search.emarefa.net/detail/BIM-1158157
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Sun, Liping& Wang, Dandan& Xu, Yan& Qi, Wenxiu& Wang, Yanbo. Evidence of TCM Theory in Treating the Same Disease with Different Methods: Treatment of Pneumonia with Ephedra sinica and Scutellariae Radix as an Example. Evidence-Based Complementary and Alternative Medicine. 2020. Vol. 2020, no. 2020, pp.1-23.
https://search.emarefa.net/detail/BIM-1158157
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1158157
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر