A Wearable Iron-Based Implant as an Intramedullary Nail in Tibial Shaft Fracture of Sheep

الملخص EN

A stable repaired fracture is the key factor responsible for the recovery of a damaged bone.

The iron-based implant is one of the biodegradable metals that have been proven safe as a fracture fixation device.

The objective of our experimental approach was to examine the potential of the iron-based implant as a biodegradable metal in tibia shaft fracture in sheep chronically.

The samples used for this experiment were iron-based and stainless steel implants.

Each had a diameter of 5 mm.

These samples were analyzed through 3 phases which are material characterization, in vitro and in vivo examination.

The samples were examined using a scanning electron microscope with energy dispersive spectrometer and X-ray diffraction.

Based on the analysis carried out, the samples contained 90,02% and 60,81% Fe for iron-based implant and stainless implant, respectively.

Both implants maintained high viability when being in contact with calf pulmonary artery endothelial cells, indicating that both implants had a minimum response to the cell in a hemocytometer and methyl tetrazolium (MTT) assay.

The systemic effect of the implants was observed using hematology and blood chemistry examination.

Data collection also shows that both implants also had a minimum response to the erythrocytes, leucocytes, blood chemistry, and blood mineral during the period of observation.

Therefore, it could be concluded that the iron-based implant is tolerable for a period of 9 months.

It also has the potential to be used as a biodegradable orthopedic implant.