A Wearable Iron-Based Implant as an Intramedullary Nail in Tibial Shaft Fracture of Sheep
Joint Authors
Siallagan, Sitaria F.
Silalahi, Marzuki
Boediono, Arief
Estuningsih, Sri
Noviana, Deni
Source
International Journal of Biomaterials
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-03-03
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
A stable repaired fracture is the key factor responsible for the recovery of a damaged bone.
The iron-based implant is one of the biodegradable metals that have been proven safe as a fracture fixation device.
The objective of our experimental approach was to examine the potential of the iron-based implant as a biodegradable metal in tibia shaft fracture in sheep chronically.
The samples used for this experiment were iron-based and stainless steel implants.
Each had a diameter of 5 mm.
These samples were analyzed through 3 phases which are material characterization, in vitro and in vivo examination.
The samples were examined using a scanning electron microscope with energy dispersive spectrometer and X-ray diffraction.
Based on the analysis carried out, the samples contained 90,02% and 60,81% Fe for iron-based implant and stainless implant, respectively.
Both implants maintained high viability when being in contact with calf pulmonary artery endothelial cells, indicating that both implants had a minimum response to the cell in a hemocytometer and methyl tetrazolium (MTT) assay.
The systemic effect of the implants was observed using hematology and blood chemistry examination.
Data collection also shows that both implants also had a minimum response to the erythrocytes, leucocytes, blood chemistry, and blood mineral during the period of observation.
Therefore, it could be concluded that the iron-based implant is tolerable for a period of 9 months.
It also has the potential to be used as a biodegradable orthopedic implant.
American Psychological Association (APA)
Siallagan, Sitaria F.& Silalahi, Marzuki& Boediono, Arief& Estuningsih, Sri& Noviana, Deni. 2019. A Wearable Iron-Based Implant as an Intramedullary Nail in Tibial Shaft Fracture of Sheep. International Journal of Biomaterials،Vol. 2019, no. 2019, pp.1-10.
https://search.emarefa.net/detail/BIM-1158437
Modern Language Association (MLA)
Siallagan, Sitaria F.…[et al.]. A Wearable Iron-Based Implant as an Intramedullary Nail in Tibial Shaft Fracture of Sheep. International Journal of Biomaterials No. 2019 (2019), pp.1-10.
https://search.emarefa.net/detail/BIM-1158437
American Medical Association (AMA)
Siallagan, Sitaria F.& Silalahi, Marzuki& Boediono, Arief& Estuningsih, Sri& Noviana, Deni. A Wearable Iron-Based Implant as an Intramedullary Nail in Tibial Shaft Fracture of Sheep. International Journal of Biomaterials. 2019. Vol. 2019, no. 2019, pp.1-10.
https://search.emarefa.net/detail/BIM-1158437
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1158437