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In Vitro Antioxidant and Antidiabetic Potentials of Syzygium caryophyllatum L. Alston
المؤلفون المشاركون
Wathsara, Herath Pathiranage Thathmi
Weeratunge, Hasitha Dhananjaya
Mubarak, Mohamed Naeem Ahammadu
Godakumbura, Pahan Indika
Ranasinghe, Pathmasiri
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-15، 15ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-07-28
دولة النشر
مصر
عدد الصفحات
15
التخصصات الرئيسية
الملخص EN
Syzygium caryophyllatum L.
Alston (Family: Myrtaceae, Sinhala: Heendan) is a red-listed plant that has been used in traditional medicine in Sri Lanka for the treatment of diabetes, but it is yet to be exploited for its potential uses as a functional food or a source of supplements.
The present study focused on the evaluation of antidiabetic property of S.
caryophyllatum fruits and leaves assessing antioxidant, antiglycation, and antiamylase activities and functional mineral element composition.
The crude extracts (CR) of leaves and fruits were fractionated into hexane (Hex) ethyl acetate (EA) and aqueous (AQ) and evaluated for bioactivities along with the crude extracts.
The isolated fraction (C3) of Hex fraction of fruit showed significantly high (p<0.05) antiamylase activity with IC50 value 2.27 ± 1.81 μg/mL where the Hex fraction of fruits exhibited the IC50 value as 47.20 ± 0.3 μg/mL which was higher than acarbose (IC50: 87.96 ± 1.43 μg/mL).
The EA fraction of leaves showed highest values for DPPH radical scavenging activity, ferric reducing antioxidant power, and oxygen radical absorbance capacity.
Significantly high (p<0.05) ABTS radical scavenging activity and iron chelating activity were observed in Hex fraction of fruit.
The composition of volatiles in leaf oil was studied with GC-MS, and 58 compounds were identified.
Inductively coupled plasma-mass spectrometry data revealed the presence of biologically significant trace elements such as Fe, Zn, Mg, Cu, Se, and Sr in leaves and fruits.
It is concluded that the Hex fraction of S.
caryophyllatum fruits will be a good source for the formulation of supplements for diabetic management with further evaluation of potency and efficacy.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Wathsara, Herath Pathiranage Thathmi& Weeratunge, Hasitha Dhananjaya& Mubarak, Mohamed Naeem Ahammadu& Godakumbura, Pahan Indika& Ranasinghe, Pathmasiri. 2020. In Vitro Antioxidant and Antidiabetic Potentials of Syzygium caryophyllatum L. Alston. Evidence-Based Complementary and Alternative Medicine،Vol. 2020, no. 2020, pp.1-15.
https://search.emarefa.net/detail/BIM-1158564
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Wathsara, Herath Pathiranage Thathmi…[et al.]. In Vitro Antioxidant and Antidiabetic Potentials of Syzygium caryophyllatum L. Alston. Evidence-Based Complementary and Alternative Medicine No. 2020 (2020), pp.1-15.
https://search.emarefa.net/detail/BIM-1158564
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Wathsara, Herath Pathiranage Thathmi& Weeratunge, Hasitha Dhananjaya& Mubarak, Mohamed Naeem Ahammadu& Godakumbura, Pahan Indika& Ranasinghe, Pathmasiri. In Vitro Antioxidant and Antidiabetic Potentials of Syzygium caryophyllatum L. Alston. Evidence-Based Complementary and Alternative Medicine. 2020. Vol. 2020, no. 2020, pp.1-15.
https://search.emarefa.net/detail/BIM-1158564
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1158564
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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