Clinical Evaluation of the Safety and Effectiveness of Heptonica: A Ghanaian Hepatorestorative Polyherbal Product
المؤلفون المشاركون
Appiah, Alfred A.
Ocloo, A.
Mensah, Merlin L. K.
Mensah, Abraham Yeboah
Agyemang, A. O.
Yamile, R. C.
Thomford, K. P.
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-06-22
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
The incidence of liver diseases is increasing globally, and many patients in developing countries are resorting to the use of herbal products as treatment.
This study was aimed at establishing the safety and effectiveness outcomes for patients with deranged liver panel treated with a Ghanaian finished polyherbal product.
The product Heptonica is prepared by CPMR from three medicinal plants: Bidens pilosa, Citrus aurantifolia, and Trema orientalis.
Fifty (50) participants with clinical and biochemical signs of liver impairment were purposively recruited and treated for a period of 28 days.
Participants received Heptonica at a dose of 30 mL 8 hourly after meals for the treatment period.
Clinical and biochemical evaluation (liver panel test, renal function test, haematology, and urinalysis) of subjects for the safety and effectiveness of the product was undertaken at days 0 (baseline), 14, and 28.
Compared to the baseline values, Heptonica did not have any untoward effect on renal function, haematological parameters, and urine parameters of subjects.
Clinical and liver panel results of the participants also improved compared to the baseline: serum aspartate transaminase (AST) (p < 0.0001), alanine transaminase (ALT) (p < 0.0001), gamma-glutamyltransferase (GGT) (p- 0.0013), total bilirubin (p-0.0136), direct bilirubin (p < 0.0001), total proteins (p-0.0409), and alkaline phosphates (p- 0.0284).
Level of albumin showed no significant difference within the study period.
The outcome of this study indicates Heptonica has hepatorestorative action with no observable toxicity and can be used with confidence as indicated as a liver tonic.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Agyemang, A. O.& Mensah, Merlin L. K.& Yamile, R. C.& Ocloo, A.& Appiah, Alfred A.& Mensah, Abraham Yeboah…[et al.]. 2020. Clinical Evaluation of the Safety and Effectiveness of Heptonica: A Ghanaian Hepatorestorative Polyherbal Product. Evidence-Based Complementary and Alternative Medicine،Vol. 2020, no. 2020, pp.1-9.
https://search.emarefa.net/detail/BIM-1158623
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Agyemang, A. O.…[et al.]. Clinical Evaluation of the Safety and Effectiveness of Heptonica: A Ghanaian Hepatorestorative Polyherbal Product. Evidence-Based Complementary and Alternative Medicine No. 2020 (2020), pp.1-9.
https://search.emarefa.net/detail/BIM-1158623
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Agyemang, A. O.& Mensah, Merlin L. K.& Yamile, R. C.& Ocloo, A.& Appiah, Alfred A.& Mensah, Abraham Yeboah…[et al.]. Clinical Evaluation of the Safety and Effectiveness of Heptonica: A Ghanaian Hepatorestorative Polyherbal Product. Evidence-Based Complementary and Alternative Medicine. 2020. Vol. 2020, no. 2020, pp.1-9.
https://search.emarefa.net/detail/BIM-1158623
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1158623
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر