Emergency Combination of Four Drugs for Bloodstream Infection Caused by Carbapenem-Resistant Enterobacteriaceae in Severe Agranulocytosis Patients with Hematologic Malignancies after Hematopoietic Stem Cell Transplantation
المؤلفون المشاركون
Li, Xiaofan
Li, Nainong
Hong, Yaqun
Chen, Xianling
Chen, Ping
المصدر
Emergency Medicine International
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-08-04
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Bloodstream infection (BSI) caused by multidrug-resistant (MDR) bacteria or extensively drug-resistant (XDR) bacteria is a global threat.
However, an effective treatment regimen is still controversial and inadequate due to the rapid deterioration caused by the bacteria.
In immunocompromised and neutropenic patients, MDR-BSI is an emergency, which causes treatment-related mortality.
In this study, four agranulocytosis patients with hematologic malignancies after HSCT receiving treatment for carbapenem-resistant Enterobacteriaceae- (CRE-) BSI were included.
Conventional treatment using two to three combined antibiotics was administered in the first and second patients.
Combination treatment using four drugs, polymyxin B, high-dose tigecycline, fosfomycin, and double-dose carbapenem, was administered in the third and fourth patients.
None of the patients receiving conventional treatment survived.
Both patients receiving combination treatment using four drugs survived.
Therefore, four-drug combination therapy may be needed in CRE-BSI patients who experienced severe agranulocytosis after HSCT.
The efficacy of the four-drug combination treatment for CRE-BSI patients as well as the adverse effects need to be further studied.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Li, Xiaofan& Hong, Yaqun& Chen, Xianling& Chen, Ping& Li, Nainong. 2020. Emergency Combination of Four Drugs for Bloodstream Infection Caused by Carbapenem-Resistant Enterobacteriaceae in Severe Agranulocytosis Patients with Hematologic Malignancies after Hematopoietic Stem Cell Transplantation. Emergency Medicine International،Vol. 2020, no. 2020, pp.1-8.
https://search.emarefa.net/detail/BIM-1159184
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Li, Xiaofan…[et al.]. Emergency Combination of Four Drugs for Bloodstream Infection Caused by Carbapenem-Resistant Enterobacteriaceae in Severe Agranulocytosis Patients with Hematologic Malignancies after Hematopoietic Stem Cell Transplantation. Emergency Medicine International No. 2020 (2020), pp.1-8.
https://search.emarefa.net/detail/BIM-1159184
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Li, Xiaofan& Hong, Yaqun& Chen, Xianling& Chen, Ping& Li, Nainong. Emergency Combination of Four Drugs for Bloodstream Infection Caused by Carbapenem-Resistant Enterobacteriaceae in Severe Agranulocytosis Patients with Hematologic Malignancies after Hematopoietic Stem Cell Transplantation. Emergency Medicine International. 2020. Vol. 2020, no. 2020, pp.1-8.
https://search.emarefa.net/detail/BIM-1159184
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1159184
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر