![](/images/graphics-bg.png)
Effects of Vonoprazan Compared with Esomeprazole on the Healing of Artificial Postendoscopic Submucosal Dissection Ulcers: A Prospective, Multicenter, Two-Arm, Randomized Controlled Trial
المؤلفون المشاركون
Sue, Soichiro
Maeda, Shin
Sasaki, Tomohiko
Kaneko, Hiroaki
Tamura, Toshihide
Kondo, Masaaki
Ishii, Yasuaki
Yamada, Hiroaki
Sato, Takeshi
Irie, Kuniyasu
Ikeda, Ryosuke
Fukuchi, Takehide
Kobayashi, Ryosuke
Makazu, Makomo
Sato, Chiko
Hirasawa, Kingo
Shibata, Wataru
المصدر
Gastroenterology Research and Practice
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-02-18
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Background.
Vonoprazan affords more clinical benefits than proton pump inhibitors (PPIs) during the healing of gastroduodenal ulcers.
However, it remains controversial whether vonoprazan is more effective than PPIs when used to heal artificial ulcers arising after endoscopic submucosal dissection (ESD).
Aim.
This study investigated the effects of vonoprazan compared with esomeprazole on the healing of post-ESD artificial ulcers.
Methods.
Sixty patients who underwent gastric ESD between May 2015 and May 2017 were randomized to treatment with vonoprazan (V group) or esomeprazole (E group) for 8 weeks.
Upper endoscopy was performed at 4 and 8 weeks after ESD, and drug effects were estimated based on the ulcer healing rates and shrinkage rates.
Results.
Fifty-three patients were analyzed.
The respective 4- and 8-week ulcer healing rates did not differ significantly between V and E groups (8.0 versus 11.5%, P=0.669; 88.9 versus 84.6%, P=0.420).
Similarly, the respective 4- and 8-week ulcer shrinkage rates did not differ significantly between V and E groups (96.8 versus 97.5%, P=0.656; 100 versus 100%, P=0.257).
Conclusion.
The healing of artificial ulcers after ESD did not differ using vonoprazan or esomeprazole.
Both vonoprazan and esomeprazole were effective when used to promote artificial ulcer healing after ESD.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Ishii, Yasuaki& Yamada, Hiroaki& Sato, Takeshi& Sue, Soichiro& Kaneko, Hiroaki& Irie, Kuniyasu…[et al.]. 2018. Effects of Vonoprazan Compared with Esomeprazole on the Healing of Artificial Postendoscopic Submucosal Dissection Ulcers: A Prospective, Multicenter, Two-Arm, Randomized Controlled Trial. Gastroenterology Research and Practice،Vol. 2018, no. 2018, pp.1-6.
https://search.emarefa.net/detail/BIM-1159253
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Ishii, Yasuaki…[et al.]. Effects of Vonoprazan Compared with Esomeprazole on the Healing of Artificial Postendoscopic Submucosal Dissection Ulcers: A Prospective, Multicenter, Two-Arm, Randomized Controlled Trial. Gastroenterology Research and Practice No. 2018 (2018), pp.1-6.
https://search.emarefa.net/detail/BIM-1159253
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Ishii, Yasuaki& Yamada, Hiroaki& Sato, Takeshi& Sue, Soichiro& Kaneko, Hiroaki& Irie, Kuniyasu…[et al.]. Effects of Vonoprazan Compared with Esomeprazole on the Healing of Artificial Postendoscopic Submucosal Dissection Ulcers: A Prospective, Multicenter, Two-Arm, Randomized Controlled Trial. Gastroenterology Research and Practice. 2018. Vol. 2018, no. 2018, pp.1-6.
https://search.emarefa.net/detail/BIM-1159253
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1159253
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
![](/images/ebook-kashef.png)
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
![](/images/kashef-image.png)