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Gastric Cancer Maximum Tumour Diameter Reduction Rate at CT Examination as a Radiological Index for Predicting Histopathological Regression after Neoadjuvant Treatment: A Multicentre GIRCG Study
المؤلفون المشاركون
Volterrani, Luca
Mazzei, Francesco Giuseppe
Roviello, Franco
Mazzei, Maria Antonietta
Marrelli, Daniele
Gentili, Francesco
Baiocchi, Gian Luca
Bagnacci, Giulio
Nigri, Andrea
Pelini, Veronica
Vindigni, Carla
Pittiani, Frida
Morgagni, Paolo
Petrella, Enrico
Mura, Gianni
Verdelli, Beatrice
Bencivenga, Maria
Giacopuzzi, Simone
المصدر
Gastroenterology Research and Practice
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-03-15
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
Aim.
To investigate the role of maximum tumour diameter (D-max) reduction rate at CT examination in predicting histopathological tumour regression grade (TRG according to the Becker grade), after neoadjuvant chemotherapy (NAC), in patients with resectable advanced gastric cancer (AGC).
Materials and Methods.
Eighty-six patients (53 M, mean age 62.1 years) with resectable AGC (≥T3 or N+), treated with NAC and radical surgery, were enrolled from 5 centres of the Italian Research Group for Gastric Cancer (GIRCG).
Staging and restaging CT and histological results were retrospectively reviewed.
CT examinations were contrast enhanced, and the stomach was previously distended.
The D-max was measured using 2D software and compared with Becker TRG.
Statistical data were obtained using “R” software.
Results.
The interobserver agreement was good/very good.
Becker TRG was predicted by CT with a sensitivity and specificity, respectively, of 97.3% and 90.9% for Becker 1 (D-max reduction rate > 65.1%), 76.4% and 80% for Becker 3 (D-max reduction rate < 29.9%), and 70.8% and 83.9% for Becker 2.
Correlation between radiological and histological D-max measurements was strongly confirmed by the correlation index (c.i.= 0.829).
Conclusions.
D-max reduction rate in AGC patients may be helpful as a simple and reproducible radiological index in predicting TRG after NAC.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Mazzei, Maria Antonietta& Bagnacci, Giulio& Gentili, Francesco& Nigri, Andrea& Pelini, Veronica& Vindigni, Carla…[et al.]. 2018. Gastric Cancer Maximum Tumour Diameter Reduction Rate at CT Examination as a Radiological Index for Predicting Histopathological Regression after Neoadjuvant Treatment: A Multicentre GIRCG Study. Gastroenterology Research and Practice،Vol. 2018, no. 2018, pp.1-10.
https://search.emarefa.net/detail/BIM-1159294
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Mazzei, Maria Antonietta…[et al.]. Gastric Cancer Maximum Tumour Diameter Reduction Rate at CT Examination as a Radiological Index for Predicting Histopathological Regression after Neoadjuvant Treatment: A Multicentre GIRCG Study. Gastroenterology Research and Practice No. 2018 (2018), pp.1-10.
https://search.emarefa.net/detail/BIM-1159294
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Mazzei, Maria Antonietta& Bagnacci, Giulio& Gentili, Francesco& Nigri, Andrea& Pelini, Veronica& Vindigni, Carla…[et al.]. Gastric Cancer Maximum Tumour Diameter Reduction Rate at CT Examination as a Radiological Index for Predicting Histopathological Regression after Neoadjuvant Treatment: A Multicentre GIRCG Study. Gastroenterology Research and Practice. 2018. Vol. 2018, no. 2018, pp.1-10.
https://search.emarefa.net/detail/BIM-1159294
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1159294
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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