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Continuous Use of Combined Hormonal Contraceptive and the Effect on Blood Coagulation Factors in Female Capuchin Monkeys (Sapajus libidinosus)
المؤلفون المشاركون
Tavares, Maria Clotilde H.
Rodrigues, Rosângela Correa
Belham, Flávia Schechtman
Garcia, Ana
Satler, Corina
Tomaz, Carlos
المصدر
International Journal of Endocrinology
العدد
المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2019-03-13
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
This study aimed at evaluating the availability of the primate Sapajus libidinosus as an animal model for research assessing the physiological effects of the continuous use of combined hormonal contraceptives.
In order to do this, six reproductively active female S.
libidinosus from the Primate Research Center of the University of Brasília were selected to take part in this experiment.
Every 21 days or so, each female received a single dose of combined hormonal contraceptive (algestone acetophenide and 17-enanthate estradiol) in a total of five doses throughout the experiment.
The physiological parameters were accessed by means of 13 blood samples from each female, whereas three were gathered during the baseline and 10 samples were collected during the treatment phase.
The results showed that the contraceptive use provoked changes in hematological coagulation factors such as an increase in the amount of platelets (p=0.039) and a reduction in both prothrombin (p<0.001) and thromboplastin coagulation time (p<0.001).
These results are similar to what has been observed in human patients; thus, it is concluded that S.
libidinosus can be successfully used in studies about the physiological impact of hormonal contraceptives.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Rodrigues, Rosângela Correa& Belham, Flávia Schechtman& Garcia, Ana& Satler, Corina& Tomaz, Carlos& Tavares, Maria Clotilde H.. 2019. Continuous Use of Combined Hormonal Contraceptive and the Effect on Blood Coagulation Factors in Female Capuchin Monkeys (Sapajus libidinosus). International Journal of Endocrinology،Vol. 2019, no. 2019, pp.1-9.
https://search.emarefa.net/detail/BIM-1159360
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Rodrigues, Rosângela Correa…[et al.]. Continuous Use of Combined Hormonal Contraceptive and the Effect on Blood Coagulation Factors in Female Capuchin Monkeys (Sapajus libidinosus). International Journal of Endocrinology No. 2019 (2019), pp.1-9.
https://search.emarefa.net/detail/BIM-1159360
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Rodrigues, Rosângela Correa& Belham, Flávia Schechtman& Garcia, Ana& Satler, Corina& Tomaz, Carlos& Tavares, Maria Clotilde H.. Continuous Use of Combined Hormonal Contraceptive and the Effect on Blood Coagulation Factors in Female Capuchin Monkeys (Sapajus libidinosus). International Journal of Endocrinology. 2019. Vol. 2019, no. 2019, pp.1-9.
https://search.emarefa.net/detail/BIM-1159360
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1159360
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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