Risk Factors Associated with the Occurrence of Autoimmune Diseases in Adult Coeliac Patients
المؤلفون المشاركون
Annibale, Bruno
Conti, Laura
Lahner, Edith
Galli, Gloria
Esposito, Gianluca
Carabotti, Marilia
المصدر
Gastroenterology Research and Practice
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-09-12
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Objectives.
Autoimmune diseases (AD) may be associated with coeliac disease (CD), but specific risk factors have been poorly investigated.
The aim of this study was to assess the spectrum of AD and its specific risk factors associated in a series of adult coeliac patients.
Materials and Methods.
We performed a single-center case-control study including adult newly diagnosed CD patients.
To evaluate the risk factors of the association between AD and CD, 341 coeliac patients included were categorized on the basis of AD presence: 91 cases with at least one AD and 250 controls without AD were compared for clinical, serological, and histological features.
Eighty-seven cases were age-gender-matched with 87 controls.
Results.
Among 341 CD patients, 26.6% of CD patients had at least one AD.
Endocrine and dermatological diseases were the most prevalent AD encountered: autoimmune thyroiditis was present in 48.4% of cases, psoriasis in 17.6%, and type I diabetes and dermatitis herpetiformis in 11%, respectively.
At logistic regression, factors associated with AD were a positive 1st-degree family history of AD (OR 3.7, 95% CI 1.93–7), a body mass index ≥ 25 kg/m2 at CD diagnosis (OR 2.95%, CI 1.1–3.8), and long standing presentation signs/symptoms before CD diagnosis (>10 years) (OR 2.1, 95% CI 1.1–3.7).
Analysis on age-gender-matched patients confirmed these results.
Conclusions.
CD patients with family history of AD, overweight at CD diagnosis, and a delay of CD diagnosis had an increased risk of having another AD.
The benefit of CD screening in these specific subsets of patients with AD awaits further investigation.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Conti, Laura& Lahner, Edith& Galli, Gloria& Esposito, Gianluca& Carabotti, Marilia& Annibale, Bruno. 2018. Risk Factors Associated with the Occurrence of Autoimmune Diseases in Adult Coeliac Patients. Gastroenterology Research and Practice،Vol. 2018, no. 2018, pp.1-6.
https://search.emarefa.net/detail/BIM-1159485
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Conti, Laura…[et al.]. Risk Factors Associated with the Occurrence of Autoimmune Diseases in Adult Coeliac Patients. Gastroenterology Research and Practice No. 2018 (2018), pp.1-6.
https://search.emarefa.net/detail/BIM-1159485
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Conti, Laura& Lahner, Edith& Galli, Gloria& Esposito, Gianluca& Carabotti, Marilia& Annibale, Bruno. Risk Factors Associated with the Occurrence of Autoimmune Diseases in Adult Coeliac Patients. Gastroenterology Research and Practice. 2018. Vol. 2018, no. 2018, pp.1-6.
https://search.emarefa.net/detail/BIM-1159485
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1159485
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر