Correlation of Serum 1,5-AG with Uric Acid in Type 2 Diabetes Mellitus with Different Renal Functions

المؤلفون المشاركون

Zhang, Kai
Xue, Bizhen
Yuan, Yuexing
Wang, Yao

المصدر

International Journal of Endocrinology

العدد

المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-7، 7ص.

الناشر

Hindawi Publishing Corporation

تاريخ النشر

2019-03-06

دولة النشر

مصر

عدد الصفحات

7

التخصصات الرئيسية

الأحياء

الملخص EN

Aim.

Recent studies found that levels of serum uric acid (SUA) were positively associated with serum 1,5-anhydroglucitol (1,5-AG) in subjects with type 2 diabetes mellitus (T2DM).

In the current study, we investigated the association between 1,5-AG and UA in T2DM patients with different renal functions.

Methods.

A total of 405 T2DM patients, 213 men and 192 women, participated in the study.

Patients’ clinical information was collected, and serum 1,5-AG, SUA, and other clinical characteristics were measured.

Correlation analyses were carried out to analyze their correlation with serum 1,5-AG and SUA.

Results.

The male group showed higher levels of SUA than the female group (282.1 ± 91.2 and 244.7 ± 71.89 μmol/L, respectively, P<0.01).

Pearson’s correlation coefficients determine that SUA was positively associated with 1,5-AG in both men (r=0.213, P<0.05) and women (r=0.223, P<0.05), and such relationship can be influenced by the renal function.

The positive association still existed with moderate impaired renal function.

Moreover, 1,5-AG had a negative association with haemoglobin A1c (HbA1c) in T2DM subjects with eGFR ≥ 30 mL/min/1.73 m2 (P<0.01).

Conclusion.

The positive association between SUA and 1,5-AG still exists in T2DM with moderate renal failure.

1,5-AG can still reflect the glucose levels in patients with CKD stages 1-3.

نمط استشهاد جمعية علماء النفس الأمريكية (APA)

Zhang, Kai& Xue, Bizhen& Yuan, Yuexing& Wang, Yao. 2019. Correlation of Serum 1,5-AG with Uric Acid in Type 2 Diabetes Mellitus with Different Renal Functions. International Journal of Endocrinology،Vol. 2019, no. 2019, pp.1-7.
https://search.emarefa.net/detail/BIM-1159531

نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)

Zhang, Kai…[et al.]. Correlation of Serum 1,5-AG with Uric Acid in Type 2 Diabetes Mellitus with Different Renal Functions. International Journal of Endocrinology No. 2019 (2019), pp.1-7.
https://search.emarefa.net/detail/BIM-1159531

نمط استشهاد الجمعية الطبية الأمريكية (AMA)

Zhang, Kai& Xue, Bizhen& Yuan, Yuexing& Wang, Yao. Correlation of Serum 1,5-AG with Uric Acid in Type 2 Diabetes Mellitus with Different Renal Functions. International Journal of Endocrinology. 2019. Vol. 2019, no. 2019, pp.1-7.
https://search.emarefa.net/detail/BIM-1159531

نوع البيانات

مقالات

لغة النص

الإنجليزية

الملاحظات

Includes bibliographical references

رقم السجل

BIM-1159531