Subchronic Infection of Porphyromonas gingivalis and Tannerella forsythia Stimulates an Immune Response but Not Arthritis in Experimental Murine Model
المؤلفون المشاركون
de la Garza-Ramos, Myriam Angelica
Hernández-Aguas, Jorday
Montiel-Hernández, José Luis
Ruiz-Ramos, Rosa Velia
Escamilla García, Erandi
Guzmán-García, Mario Alberto
Ayón-Haro, Esperanza Raquel
Garza-Elizondo, Mario Alberto
المصدر
International Journal of Dentistry
العدد
المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2017-06-06
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Studies have proposed that Porphyromonas gingivalis (Pg) and Tannerella forsythia (Tf) promote a nonspecific inflammatory response that could produce systemic disease.
Oral inoculation of Pg and Tf on the immune and arthritis response was evaluated in BALB/C mice divided into four groups: (1) sham; (2) food contaminated with Pg/Tf; (3) complete Freund’s adjuvant (CFA) + Pg/Tf; and (4) CFA alone.
CFA was administered subcutaneously on days 1 and 14.
The arthritis response was monitored for 21 days after day 14 of CFA administration.
IL-1β and IL-6 were determined in serum.
T cell activation was evaluated by CD25 in salivary lymph nodes or mouse spleen.
Pad inflammation appeared by day 19 in the CFA group, but animals with bacteria inoculation presented a delay.
A significant increase in IL-6 was found in Groups 3 and 4, but not with respect to IL-1β.
We observed an increase in CD25 in cells derived from cervical nodes and in animals with bacteria inoculation and CFA.
A local immune response was observed in mice inoculated with Pg and Tf (T cell activation); a systemic response was observed with CFA.
Since pad inflammation was delayed by bacterial inoculation this suggests that local T cell activation could decrease pad inflammation.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Hernández-Aguas, Jorday& Montiel-Hernández, José Luis& de la Garza-Ramos, Myriam Angelica& Ruiz-Ramos, Rosa Velia& Escamilla García, Erandi& Guzmán-García, Mario Alberto…[et al.]. 2017. Subchronic Infection of Porphyromonas gingivalis and Tannerella forsythia Stimulates an Immune Response but Not Arthritis in Experimental Murine Model. International Journal of Dentistry،Vol. 2017, no. 2017, pp.1-7.
https://search.emarefa.net/detail/BIM-1165487
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Hernández-Aguas, Jorday…[et al.]. Subchronic Infection of Porphyromonas gingivalis and Tannerella forsythia Stimulates an Immune Response but Not Arthritis in Experimental Murine Model. International Journal of Dentistry No. 2017 (2017), pp.1-7.
https://search.emarefa.net/detail/BIM-1165487
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Hernández-Aguas, Jorday& Montiel-Hernández, José Luis& de la Garza-Ramos, Myriam Angelica& Ruiz-Ramos, Rosa Velia& Escamilla García, Erandi& Guzmán-García, Mario Alberto…[et al.]. Subchronic Infection of Porphyromonas gingivalis and Tannerella forsythia Stimulates an Immune Response but Not Arthritis in Experimental Murine Model. International Journal of Dentistry. 2017. Vol. 2017, no. 2017, pp.1-7.
https://search.emarefa.net/detail/BIM-1165487
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1165487
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر