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Arterial Hemodynamics in Prehypertensives
المؤلفون المشاركون
Ting, Chih-Tai
Chen, Jaw-Wen
Chang, Mau-Song
Yin, Frank Chi-Pong
المصدر
International Journal of Hypertension
العدد
المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2019-04-01
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Compared to age-matched normotensive adults, those with essential hypertension have been shown to have distinct arterial hemodynamic abnormalities consisting of increased peripheral resistance, pulse wave velocity, and wave reflection magnitude as well as decreased wave reflection time and aortic compliance.
These abnormalities are further exacerbated by beta-adrenergic blockade.
To see if there are similar hemodynamic abnormalities that antedate the onset of fixed hypertension, we compared age-matched normotensives with prehypertensives selected from patients undergoing diagnostic cardiac catheterization.
Ascending aortic pressure and flow were measured with a micromanometer and flow velocity sensor in the baseline state and after beta-adrenergic blockade.
In the baseline state the prehypertensive compared to the normotensive group had elevated blood pressure, resistance, left ventricular end-diastolic pressure (LVEDP), and wave reflections.
Beta-adrenergic blockade increased resistance, LVEDP, and wave reflections in both groups.
Some of these findings are the same as those we previously reported in young persons with established, essential hypertension.
The differences in LVEDP and wave reflections, both in the baseline state and after beta-blockade, were still present in subgroups with no differences in blood pressure.
Hence, the elevated wave reflections in prehypertensives do not appear to be directly related to the level of blood pressure.
These results support the notion that the elevated blood pressure in hypertension may represent a later manifestation of an already abnormal vascular system rather than the vascular abnormalities resulting from hypertension.
Consequently, even before blood pressure becomes elevated, early diagnosis and treatment of the vascular abnormalities in prehypertensives may be warranted.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Ting, Chih-Tai& Chen, Jaw-Wen& Chang, Mau-Song& Yin, Frank Chi-Pong. 2019. Arterial Hemodynamics in Prehypertensives. International Journal of Hypertension،Vol. 2019, no. 2019, pp.1-9.
https://search.emarefa.net/detail/BIM-1166003
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Ting, Chih-Tai…[et al.]. Arterial Hemodynamics in Prehypertensives. International Journal of Hypertension No. 2019 (2019), pp.1-9.
https://search.emarefa.net/detail/BIM-1166003
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Ting, Chih-Tai& Chen, Jaw-Wen& Chang, Mau-Song& Yin, Frank Chi-Pong. Arterial Hemodynamics in Prehypertensives. International Journal of Hypertension. 2019. Vol. 2019, no. 2019, pp.1-9.
https://search.emarefa.net/detail/BIM-1166003
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1166003
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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