GH Responsiveness to Combined GH-Releasing Hormone and Arginine Administration in Obese Patients with Fibromyalgia Syndrome
المؤلفون المشاركون
Sartorio, Alessandro
Grugni, Graziano
Arreghini, Marco
Capodaglio, Paolo
De Col, Alessandra
Rigamonti, Antonello E.
Agosti, Fiorenza
المصدر
International Journal of Endocrinology
العدد
المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2017-06-28
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Reportedly, fibromyalgia (FM) is frequently associated with reduced IGF-1 levels and GH hyporesponsiveness to different GH stimulation tests.
Since there is a high prevalence of obesity in FM, and obesity itself is characterized by hyposomatotropism, the aim of this study was to assess IGF-1 levels and GH responsiveness in sixteen severely obese women suffering from FM, who, subdivided into two subgroups on the basis of their age-dependent IGF-1 values (> or <−2 SDS), underwent the combined GHRH plus arginine test.
Four out of 16 obese women with FM (25%) had low IGF-1 SDS values, 2 cases of this subgroup (12.5%) failing also to normally respond to the test.
Among patients with normal GH responses, 4 showed a delayed GH peak.
The subgroup with low IGF-1 SDS values had higher BMI than that with normal IGF-1 SDS.
GH peak and area under the curve were not correlated with CRP, ESR, or tender point score, while significant correlations were found with fat-free mass and fat mass.
In conclusion, this study shows the existence of a high prevalence of GH-IGF-1 dysfunction in patients with both FM and obesity, presumably as a consequence of the obese rather than fibromyalgic condition.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Rigamonti, Antonello E.& Grugni, Graziano& Arreghini, Marco& Capodaglio, Paolo& De Col, Alessandra& Agosti, Fiorenza…[et al.]. 2017. GH Responsiveness to Combined GH-Releasing Hormone and Arginine Administration in Obese Patients with Fibromyalgia Syndrome. International Journal of Endocrinology،Vol. 2017, no. 2017, pp.1-6.
https://search.emarefa.net/detail/BIM-1166123
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Rigamonti, Antonello E.…[et al.]. GH Responsiveness to Combined GH-Releasing Hormone and Arginine Administration in Obese Patients with Fibromyalgia Syndrome. International Journal of Endocrinology No. 2017 (2017), pp.1-6.
https://search.emarefa.net/detail/BIM-1166123
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Rigamonti, Antonello E.& Grugni, Graziano& Arreghini, Marco& Capodaglio, Paolo& De Col, Alessandra& Agosti, Fiorenza…[et al.]. GH Responsiveness to Combined GH-Releasing Hormone and Arginine Administration in Obese Patients with Fibromyalgia Syndrome. International Journal of Endocrinology. 2017. Vol. 2017, no. 2017, pp.1-6.
https://search.emarefa.net/detail/BIM-1166123
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1166123
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر