Thickness of Extraocular Muscle and Orbital Fat in MRI Predicts Response to Glucocorticoid Therapy in Graves’ Ophthalmopathy
المؤلفون المشاركون
Xu, Lingling
Xie, Cuihua
Guan, Meiping
Li, Linna
Xue, Yaoming
المصدر
International Journal of Endocrinology
العدد
المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2017-08-06
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
33 patients with active, moderate-severe Graves’ ophthalmopathy (GO) received 4.5 g methylprednisolone for 12 weeks and were divided by efficacy into two groups (responsive and unresponsive).
All patients and 10 controls underwent orbital MRI examination at baseline.
No significant difference was seen in baseline clinical characteristics between the two GO groups.
The values of exophthalmos were higher in both GO groups than in the control and were higher in the responsive group versus the unresponsive group.
Compared to the unresponsive group, the responsive group had a thicker inferior rectus as well as thinner orbital fat.
The inferior rectus/fat ratio was significantly higher in the responsive group versus the unresponsive group.
Multivariate logistic regression analysis showed that the exophthalmos value and inferior rectus/fat ratio were significantly associated with the response to glucocorticoid (GC).
ROC analysis revealed that the cut-off points of the inferior rectus/fat ratio combined with the exophthalmos value to indicate efficacy were 1.42 and 20.78.
For moderate-severe GO patients with CAS > 3, the combined inferior rectus/fat ratio and exophthalmos value in MRI may be a valuable indicator to predict the response to GC therapy.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Xu, Lingling& Li, Linna& Xie, Cuihua& Guan, Meiping& Xue, Yaoming. 2017. Thickness of Extraocular Muscle and Orbital Fat in MRI Predicts Response to Glucocorticoid Therapy in Graves’ Ophthalmopathy. International Journal of Endocrinology،Vol. 2017, no. 2017, pp.1-8.
https://search.emarefa.net/detail/BIM-1166135
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Xu, Lingling…[et al.]. Thickness of Extraocular Muscle and Orbital Fat in MRI Predicts Response to Glucocorticoid Therapy in Graves’ Ophthalmopathy. International Journal of Endocrinology No. 2017 (2017), pp.1-8.
https://search.emarefa.net/detail/BIM-1166135
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Xu, Lingling& Li, Linna& Xie, Cuihua& Guan, Meiping& Xue, Yaoming. Thickness of Extraocular Muscle and Orbital Fat in MRI Predicts Response to Glucocorticoid Therapy in Graves’ Ophthalmopathy. International Journal of Endocrinology. 2017. Vol. 2017, no. 2017, pp.1-8.
https://search.emarefa.net/detail/BIM-1166135
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1166135
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر