![](/images/graphics-bg.png)
Analysis of Correlation between the Seven Important Helicobacter pylori (H. pylori) Virulence Factors and Drug Resistance in Patients with Gastritis
المؤلفون المشاركون
Sezerman, Ugur
Kilic, Elif
Oktem-Okullu, Sinem
Cekic-Kipritci, Zehra
Seymen, Nogayhan
Mansur-Ozen, Nesteren
Gurol, Yesim
المصدر
Gastroenterology Research and Practice
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-08-29
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
The aim of this study is to evaluate the association between seven important H.
pylori virulence factors and antibiotic resistance in patients with gastritis.
H.
pylori strains isolated from 33 patients with gastritis were examined.
Antimicrobial susceptibilities were tested by GenoType® HelicoDR (Hain Life Science, Germany) test kit and RT-PCR.
The virulence-factors were determined using conventional PCR.
39% of patients were resistant for clarithromycin and 27% of patients were resistant for fluoroquinolone.
15% of patients were resistant to both clarithromycin and fluoroquinolone.
The H.
pylori vacA m1/s2 genotype was the most frequent allelic combination.
Patients were possessed the vacA s1, m1 (6.1%); s1, m2 (6.1%); s2, m1 (15.1%); and s2, m2 (3.0%) genotypes.
94% of patients with gastritis were positive for H.
pylori napA gene.
Also, there were no dupA gene-positive gastritis patients.
There was no significant correlation between the vacA, cagA, oipA, hpaA, babA, napA, dupA, ureA, ureB virulence genes, clarithromycin, and fluoroquinolone resistance.
Herein, we report that the relationship between the H.
pylori napA gene and gastritis.
Although we found a correlation between H.
pylori virulence factor and clinical outcome, there is a need for further studies to enlighten the relation between H.
pylori virulence genes and antibiotic resistance.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Oktem-Okullu, Sinem& Cekic-Kipritci, Zehra& Kilic, Elif& Seymen, Nogayhan& Mansur-Ozen, Nesteren& Sezerman, Ugur…[et al.]. 2020. Analysis of Correlation between the Seven Important Helicobacter pylori (H. pylori) Virulence Factors and Drug Resistance in Patients with Gastritis. Gastroenterology Research and Practice،Vol. 2020, no. 2020, pp.1-7.
https://search.emarefa.net/detail/BIM-1166783
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Oktem-Okullu, Sinem…[et al.]. Analysis of Correlation between the Seven Important Helicobacter pylori (H. pylori) Virulence Factors and Drug Resistance in Patients with Gastritis. Gastroenterology Research and Practice No. 2020 (2020), pp.1-7.
https://search.emarefa.net/detail/BIM-1166783
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Oktem-Okullu, Sinem& Cekic-Kipritci, Zehra& Kilic, Elif& Seymen, Nogayhan& Mansur-Ozen, Nesteren& Sezerman, Ugur…[et al.]. Analysis of Correlation between the Seven Important Helicobacter pylori (H. pylori) Virulence Factors and Drug Resistance in Patients with Gastritis. Gastroenterology Research and Practice. 2020. Vol. 2020, no. 2020, pp.1-7.
https://search.emarefa.net/detail/BIM-1166783
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1166783
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
![](/images/ebook-kashef.png)
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
![](/images/kashef-image.png)