Bacterial Diversity in the Intestinal Mucosa of Dysbiosis Diarrhea Mice Treated with Qiweibaizhu Powder
المؤلفون المشاركون
Yu, Rong
Long, Cheng-Xing
Shao, Hao-Qing
Luo, Cheng-Yu
Tan, Zhou-Jin
المصدر
Gastroenterology Research and Practice
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-01-07
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
The current research tried to explore the effect of Qiweibaizhu powder (QWBZP) on the bacterial diversity and community structure of the intestinal mucosa of dysbiosis diarrhea mice and provide a scientific basis for the efficacy of QWBZP on antibiotic-induced diarrhea.
A dysbiosis diarrhea mouse model was constructed with broad-spectrum antibiotics through a mixture of cephradine capsules and gentamicin sulfate (23.33 mL·kg-1·d-1).
Intestinal mucosa was collected, and DNA was extracted from each group.
The bacterial characteristics in intestinal mucosa were analyzed by MiSeq sequencing based on the 16S rRNA sequencing platform.
There were no significant differences in alpha diversity indices among the three groups.
The sample distributions in both the normal and QWBZP groups were relatively concentrated, and the distance among individuals was close.
However, an opposite result was obtained in the model group.
Furthermore, the composition and abundance of species were similar between the normal group and the QWBZP group at both the phylum and genus levels.
After treatment with QWBZP, the abundance of Lactobacillus increased, and Proteobacteria decreased, and the Firmicutes/Bacteroidetes ratio decreased to a normal level.
Our results indicate that QWBZP can help repair mucosal bacterial structure and recover mucosal microbiota.
Specifically, QWBZP increased the abundance of Lactobacillus and Bacteroidales S24-7 group norank.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Long, Cheng-Xing& Shao, Hao-Qing& Luo, Cheng-Yu& Yu, Rong& Tan, Zhou-Jin. 2020. Bacterial Diversity in the Intestinal Mucosa of Dysbiosis Diarrhea Mice Treated with Qiweibaizhu Powder. Gastroenterology Research and Practice،Vol. 2020, no. 2020, pp.1-8.
https://search.emarefa.net/detail/BIM-1167160
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Long, Cheng-Xing…[et al.]. Bacterial Diversity in the Intestinal Mucosa of Dysbiosis Diarrhea Mice Treated with Qiweibaizhu Powder. Gastroenterology Research and Practice No. 2020 (2020), pp.1-8.
https://search.emarefa.net/detail/BIM-1167160
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Long, Cheng-Xing& Shao, Hao-Qing& Luo, Cheng-Yu& Yu, Rong& Tan, Zhou-Jin. Bacterial Diversity in the Intestinal Mucosa of Dysbiosis Diarrhea Mice Treated with Qiweibaizhu Powder. Gastroenterology Research and Practice. 2020. Vol. 2020, no. 2020, pp.1-8.
https://search.emarefa.net/detail/BIM-1167160
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1167160
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر