Synthesis of Organic Ligands via Reactions of 4-Benzoyl-5-phenylamino-2,3-dihydrothiophene-2,3-dione with N-Nucleophiles

المؤلفون المشاركون

Kabirifard, Hassan
Hafez Taghva, Pardis
Teimouri, Hossein
Koosheshi, Niloofar
Javadpour, Parastoo
Bagherinejad, Hanieh
Seyfi, Soheila
Hossein Roodbari, Maryam
Golabian, Elaheh

المصدر

Heteroatom Chemistry

العدد

المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-9، 9ص.

الناشر

Hindawi Publishing Corporation

تاريخ النشر

2020-07-08

دولة النشر

مصر

عدد الصفحات

9

التخصصات الرئيسية

الكيمياء

الملخص EN

The reaction of 4-benzoyl-5-phenylamino-2,3-dihydrothiophene-2,3-dione (1) with aminoheteroaryls, lamotrigine, 1,3-diaminoheteroaryls, dapsone, NH2R (hydroxylamine, DL-1-phenylethylamine, and metformin), and 4,4′-bipyridine in THF/H2O (1 : 1) at room temperature led to 3-N-phenylthiocarbamoyl-2-butenamides 2–5, while that with naphthylamines and 1,3-phenylenediamine in ethanol at high temperature led to 5-phenylamino-2,5-dihydrothiophene-2-ones 6–8 as organic ligands in the medium to good yields.

These showed the nucleophilic attacks of N-nucleophiles, except primary aromatic amines, on thioester carboxyl group (C-2) of thiophene-2,3-dione ring 1.

However, the nucleophilic attacks of primary aromatic amines on the carbonyl group (C-3) of thiophene-2,3-dione 1 occurred in the form of substituted thiophenes.

نمط استشهاد جمعية علماء النفس الأمريكية (APA)

Kabirifard, Hassan& Hafez Taghva, Pardis& Teimouri, Hossein& Koosheshi, Niloofar& Javadpour, Parastoo& Bagherinejad, Hanieh…[et al.]. 2020. Synthesis of Organic Ligands via Reactions of 4-Benzoyl-5-phenylamino-2,3-dihydrothiophene-2,3-dione with N-Nucleophiles. Heteroatom Chemistry،Vol. 2020, no. 2020, pp.1-9.
https://search.emarefa.net/detail/BIM-1167218

نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)

Kabirifard, Hassan…[et al.]. Synthesis of Organic Ligands via Reactions of 4-Benzoyl-5-phenylamino-2,3-dihydrothiophene-2,3-dione with N-Nucleophiles. Heteroatom Chemistry No. 2020 (2020), pp.1-9.
https://search.emarefa.net/detail/BIM-1167218

نمط استشهاد الجمعية الطبية الأمريكية (AMA)

Kabirifard, Hassan& Hafez Taghva, Pardis& Teimouri, Hossein& Koosheshi, Niloofar& Javadpour, Parastoo& Bagherinejad, Hanieh…[et al.]. Synthesis of Organic Ligands via Reactions of 4-Benzoyl-5-phenylamino-2,3-dihydrothiophene-2,3-dione with N-Nucleophiles. Heteroatom Chemistry. 2020. Vol. 2020, no. 2020, pp.1-9.
https://search.emarefa.net/detail/BIM-1167218

نوع البيانات

مقالات

لغة النص

الإنجليزية

الملاحظات

Includes bibliographical references

رقم السجل

BIM-1167218