Alleviating Promotion of Inflammation and Cancer Induced by Nonsteroidal Anti-Inflammatory Drugs
المؤلفون المشاركون
Kyriakopoulos, Anthony M.
Nagl, Markus
Baliou, Stella
Zoumpourlis, Vassilis
المصدر
International Journal of Inflammation
العدد
المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-17، 17ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2017-05-10
دولة النشر
مصر
عدد الصفحات
17
التخصصات الرئيسية
الملخص EN
Clinical Relevance.
Nonsteroidal Anti-Inflammatory Drugs (NSAIDs) including aspirin are of intensive use nowadays.
These drugs exert their activity via the metabolism of arachidonic acid (AA) by cyclooxygenase inhibition.
Though beneficial for health in some instances, both unspecific and specific cyclooxygenase inhibitor activity interfere with AA metabolism producing also proinflammatory lipids that may promote cancer.
Materials and Methods.
This review is based on available literature on clinical uses, biochemical investigations, molecular medicine, pharmacology, toxicity, and epidemiology-clinical studies on NSAIDs and other drugs that may be used accordingly, which was collected from electronic (SciFinder, Medline, Science Direct, and ACS among others) and library searches of books and journals.
Results.
Relevant literature supports the notion that NDSAID use may also promote proinflammatory biochemical events that are also related to precancerous predisposition.
Several agents are proposed that may be employed in immediate future to supplement and optimize treatment with NSAIDs.
In this way serious side effects arising from promotion of inflammation and cancer, especially in chronic NSAID users and high risk groups of patients, could be avoided.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Kyriakopoulos, Anthony M.& Nagl, Markus& Baliou, Stella& Zoumpourlis, Vassilis. 2017. Alleviating Promotion of Inflammation and Cancer Induced by Nonsteroidal Anti-Inflammatory Drugs. International Journal of Inflammation،Vol. 2017, no. 2017, pp.1-17.
https://search.emarefa.net/detail/BIM-1167509
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Kyriakopoulos, Anthony M.…[et al.]. Alleviating Promotion of Inflammation and Cancer Induced by Nonsteroidal Anti-Inflammatory Drugs. International Journal of Inflammation No. 2017 (2017), pp.1-17.
https://search.emarefa.net/detail/BIM-1167509
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Kyriakopoulos, Anthony M.& Nagl, Markus& Baliou, Stella& Zoumpourlis, Vassilis. Alleviating Promotion of Inflammation and Cancer Induced by Nonsteroidal Anti-Inflammatory Drugs. International Journal of Inflammation. 2017. Vol. 2017, no. 2017, pp.1-17.
https://search.emarefa.net/detail/BIM-1167509
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1167509
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر