Gastrointestinal Symptoms and Elevated Levels of Anti-Saccharomyces cerevisiae Antibodies Are Associated with Higher Disease Activity in Colombian Patients with Spondyloarthritis
المؤلفون المشاركون
Romero-Sánchez, C.
Bautista-Molano, W.
Parra, V.
De Avila, J.
Rueda, J. C.
Bello-Gualtero, J. M.
Londoño, J.
Valle, R.
المصدر
International Journal of Rheumatology
العدد
المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2017-10-29
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Background.
Spondyloarthritis (SpA) is a group of articular inflammatory rheumatic diseases that their gastrointestinal manifestations are around 10% of their extra-articular symptoms, supporting that the inflammatory response of the intestinal mucosa could be associated with the clinical status.
Objectives.
To investigate the association between gastrointestinal symptoms and autoantibodies and disease activity between SpA patients, healthy subjects (HS), and patients with inflammatory bowel disease (IBD).
Methods.
102 SpA patients, 29 IBD patients, and 117 HS were included.
Autoantibodies as ASCA, ANCA, anti-tTG, anti-DGP, ANA, and IgA were measured.
The patients were assessed to evaluate clinical and gastrointestinal symptoms.
An association analysis was performed using Chi square test and a logistic regression.
Results.
Significant differences were found for ASCA levels in SpA (28.2%) compared to IBD (14.2%) and HS (6.0%) (p=0.029), as well as for ANAS in SpA (49.5%) and IBD (37.9%) (p<0.001) and abdominal pain (p=0.012) between SpA (54.3%) and IBD (27.5%).
Significant associations were found between BASDAI > 4 and gastrointestinal symptoms (p<0.05) and IgA (p=0.007).
The association for abdominal bloating was maintained (OR: 3.93, CI-95%, 1.14–13.56; p=0.030).
Conclusions.
Gastrointestinal symptoms, ASCA, ANAS, and IgA levels were associated with high disease activity in SpA compared with IBD and HS.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Romero-Sánchez, C.& Bautista-Molano, W.& Parra, V.& De Avila, J.& Rueda, J. C.& Bello-Gualtero, J. M.…[et al.]. 2017. Gastrointestinal Symptoms and Elevated Levels of Anti-Saccharomyces cerevisiae Antibodies Are Associated with Higher Disease Activity in Colombian Patients with Spondyloarthritis. International Journal of Rheumatology،Vol. 2017, no. 2017, pp.1-8.
https://search.emarefa.net/detail/BIM-1169375
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Romero-Sánchez, C.…[et al.]. Gastrointestinal Symptoms and Elevated Levels of Anti-Saccharomyces cerevisiae Antibodies Are Associated with Higher Disease Activity in Colombian Patients with Spondyloarthritis. International Journal of Rheumatology No. 2017 (2017), pp.1-8.
https://search.emarefa.net/detail/BIM-1169375
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Romero-Sánchez, C.& Bautista-Molano, W.& Parra, V.& De Avila, J.& Rueda, J. C.& Bello-Gualtero, J. M.…[et al.]. Gastrointestinal Symptoms and Elevated Levels of Anti-Saccharomyces cerevisiae Antibodies Are Associated with Higher Disease Activity in Colombian Patients with Spondyloarthritis. International Journal of Rheumatology. 2017. Vol. 2017, no. 2017, pp.1-8.
https://search.emarefa.net/detail/BIM-1169375
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1169375
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر